Literature DB >> 9453647

Adherence of Streptococcus pneumoniae to human bronchial epithelial cells (BEAS-2B).

J E Adamou1, T M Wizemann, P Barren, S Langermann.   

Abstract

Pneumococcal adherence to alveolar epithelial cells and nasopharyngeal epithelial cells has been well characterized. However, the interaction of Streptococcus pneumoniae with bronchial epithelial cells has not been studied. We have now shown that pneumococci bind specifically to a human bronchial epithelial cell line (BEAS-2B cells). Pneumococci adhered to BEAS-2B cells in a time- and dose-dependent manner. These results suggest that the bronchial epithelium may serve as an additional site of attachment for pneumococci and demonstrate the utility of the BEAS-2B cell line for studying mechanisms of pneumococcal infection.

Entities:  

Mesh:

Year:  1998        PMID: 9453647      PMCID: PMC107975     

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  17 in total

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  28 in total

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Journal:  Infect Immun       Date:  2011-12-12       Impact factor: 3.441

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Authors:  Brett R Hanson; Beth A Lowe; Melody N Neely
Journal:  J Bacteriol       Date:  2010-11-19       Impact factor: 3.490

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Journal:  Infect Immun       Date:  2013-08-05       Impact factor: 3.441

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Authors:  Sven Hammerschmidt; Sonja Wolff; Andreas Hocke; Simone Rosseau; Ellruth Müller; Manfred Rohde
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Authors:  Cynthia Olotu; Felix Lehmensiek; Bastian Koch; Martina Kiefmann; Ann-Kathrin Riegel; Sven Hammerschmidt; Rainer Kiefmann
Journal:  J Biol Chem       Date:  2019-07-09       Impact factor: 5.157

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