| Literature DB >> 9453647 |
J E Adamou1, T M Wizemann, P Barren, S Langermann.
Abstract
Pneumococcal adherence to alveolar epithelial cells and nasopharyngeal epithelial cells has been well characterized. However, the interaction of Streptococcus pneumoniae with bronchial epithelial cells has not been studied. We have now shown that pneumococci bind specifically to a human bronchial epithelial cell line (BEAS-2B cells). Pneumococci adhered to BEAS-2B cells in a time- and dose-dependent manner. These results suggest that the bronchial epithelium may serve as an additional site of attachment for pneumococci and demonstrate the utility of the BEAS-2B cell line for studying mechanisms of pneumococcal infection.Entities:
Mesh:
Year: 1998 PMID: 9453647 PMCID: PMC107975
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441