Literature DB >> 945345

Potential antitumor agents: a cytotoxic cardenolide from Coronilla varia L.

M Williams, J M Cassady.   

Abstract

An alcoholic extract of the seeds of Coronilla varia L. showed inhibitory activity against KB cells in culture and was fractionated through a series of partitions, column chromatography, and preparative layer chromatography to yield hyrcanoside, daphnoretin, scopoletin, and umbelliferone. Hyrcanoside was also tested in the PS mouse leukemia assay and showed borderline activity.

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Year:  1976        PMID： 945345     DOI： 10.1002/jps.2600650628

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  4 in total

1.  Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity.

Authors:  Silvie Rimpelová; Tomáš Zimmermann; Pavel B Drašar; Bohumil Dolenský; Jiří Bejček; Eva Kmoníčková; Petra Cihlářová; Soňa Gurská; Lucie Kuklíková; Marián Hajdůch; Tomáš Ruml; Lubomír Opletal; Petr Džubák; Michal Jurášek
Journal:  Foods       Date:  2021-01-11

2.  Antibacterial and antitumour activities of some plants grown in Turkey.

Authors:  Canan Usta; Arzu Birinci Yildirim; Arzu Ucar Turker
Journal:  Biotechnol Biotechnol Equip       Date:  2014-07-08       Impact factor: 1.632

Review 3.  Oleandrin: A cardiac glycosides with potent cytotoxicity.

Authors:  Arvind Kumar; Tanmoy De; Amrita Mishra; Arun K Mishra
Journal:  Pharmacogn Rev       Date:  2013-07

4.  The Volatile Chemical Compositions of the Essential Oil/SPME and Enzyme Inhibitory and Radical Scavenging Activities of Solvent Extracts and the Essential oils from Coronilla orientalis Miller and C. varia L. grows in Turkey.

Authors:  Gülin Renda; Arzu Özel; Burak Barut; Büşra Korkmaz; Nurettin Yayli
Journal:  Iran J Pharm Res       Date:  2019       Impact factor: 1.696
  4 in total

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