Literature DB >> 945186

Is feminine differentiation of the brain hormonally determined?

B H Shapiro, A S Goldman, H F Steinbeck, F Neumann.   

Abstract

The androgen insensitive, genetically male rat pseudohermaphrodite displays neither masculine or feminine sexual behavior when primed with the appropriate sex hormones. Although in the absence of androgen imprinting the animal develops anatomically as female, our results suggest that feminine differentiation of the brain requires active imprinting by perinatal hormone(s), possibly adrenal progesterone.

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Year:  1976        PMID: 945186     DOI: 10.1007/bf01990214

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  17 in total

1.  ROLE OF THE DEVELOPING RAT TESTIS IN DIFFERENTIATION OF THE NEURAL TISSUES MEDIATING MATING BEHAVIOR.

Authors:  K L GRADY; C H PHOENIX; W C YOUNG
Journal:  J Comp Physiol Psychol       Date:  1965-04

2.  Androgen metabolism and mechanism of action in male pseudohermaphroditism: a study of testicular feminization.

Authors:  C W Bardin; L P Bullock; R J Sherins; I Mowszowicz; W R Blackburn
Journal:  Recent Prog Horm Res       Date:  1973

3.  Metabolism of steroid hormones, sterols, and bile acids in liver microsomes from male, female, and male-pseudohermaphroditic rats.

Authors:  K Einarsson; J A Gustafsson; A S Goldman
Journal:  Eur J Biochem       Date:  1972-12-04

4.  TfM mutation and masculinization versus feminization of the mouse central nervous system.

Authors:  S Ono; L N Geller; E V Lai
Journal:  Cell       Date:  1974-11       Impact factor: 41.582

5.  Prenatal interference with the onset of puberty, vaginal cyclicity and subsequent pregnancy in the female rat.

Authors:  B H Shapiro; A S Goldman; A W Root
Journal:  Proc Soc Exp Biol Med       Date:  1974-01

6.  Prevention by progesterone of steroid-induced sterility in neonatal male and female rats.

Authors:  F A Kincl; M Maqueo
Journal:  Endocrinology       Date:  1965-11       Impact factor: 4.736

7.  The infleunce of fetal sex on plasma progesterone levels.

Authors:  F C Hagemenas; G W Kittinger
Journal:  Endocrinology       Date:  1972-07       Impact factor: 4.736

8.  Hormonal determinants of the development of masculine and feminine behavior in male and female rats.

Authors:  R E Whalen; D A Edwards
Journal:  Anat Rec       Date:  1967-02

9.  Pituitary hormone secretion in the genectically male rat pseudohermaphrodite.

Authors:  A S Goldman; A W Root; G Duckett; B H Shapiro
Journal:  J Endocrinol       Date:  1975-02       Impact factor: 4.286

10.  The "puberty" of the rat liver. Feminine pattern of cortisol metabolism in male rats castrated at birth.

Authors:  P De Moor; C Denef
Journal:  Endocrinology       Date:  1968-03       Impact factor: 4.736

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  4 in total

Review 1.  The role of androgen receptors in the masculinization of brain and behavior: what we've learned from the testicular feminization mutation.

Authors:  Damian G Zuloaga; David A Puts; Cynthia L Jordan; S Marc Breedlove
Journal:  Horm Behav       Date:  2008-02-15       Impact factor: 3.587

2.  Sexual dimorphism of newborn mouse epithalamus after fractionated X-irradiation at late stage of organogenesis.

Authors:  W Schmahl; L Weber
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1980

Review 3.  A role for the androgen receptor in the sexual differentiation of the olfactory system in mice.

Authors:  Cristian Bodo
Journal:  Brain Res Rev       Date:  2007-09-05

4.  The androgen receptor is selectively involved in organization of sexually dimorphic social behaviors in mice.

Authors:  Cristian Bodo; Emilie F Rissman
Journal:  Endocrinology       Date:  2008-05-08       Impact factor: 4.736

  4 in total

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