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Literature DB >> 9450654

The effect of anti-prolactin antibody on in vitro synthesis of a pregnancy-associated rat uterine glycoprotein.

Abstract

Experiments were conducted to study the hormonal (estrogen [E2], progesterone [P4] and prolactin [PRL]), regulation of synthesis of a pregnancy-associated glycoprotein (named Uterine Agglutinin or UA) in the Day 4 post coital (p.c.) rat uterus with antibody administration and immunohistochemistry. Of the antibodies used, it was shown that anti-PRL antibody was the most effective in reducing in vitro UA synthesis. The results suggested that in vitro UA synthesis could be correlated to serum PRL levels as analyzed by radio-immunoassay. Binding studies revealed that PRL bound specifically to the stromal cells of the rat uterus where UA is produced and localized.

Entities: Gene Species

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Year: 1997 PMID： 9450654 DOI： 10.1023/a:1006897011859

Source DB: PubMed Journal: Mol Cell Biochem ISSN： 0300-8177 Impact factor: 3.396

15 in total

1. The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy.

Authors: M S Smith; M E Freeman; J D Neill
Journal: Endocrinology Date: 1975-01 Impact factor: 4.736

2. The effect of ether and laparatomy on serum prolactin levels in progesterone-treated intact and ovariectomized rats.

Authors: P J Reier; W K Morishige; I Rothchild
Journal: Neuroendocrinology Date: 1974 Impact factor: 4.914

3. Semicircadian rhythm in plasma levels of prolactin during early gestation in the rat.

Authors: R L Butcher; N W Fugo; W E Collins
Journal: Endocrinology Date: 1972-04 Impact factor: 4.736

4. Serum prolactin levels in rats during different reproductive states.

Authors: Y Amenomori; C L Chen; J Meites
Journal: Endocrinology Date: 1970-03 Impact factor: 4.736

Review 5. Hormonal basis of maternal behavior in the rat.

Authors: H I Siegel
Journal: Ann N Y Acad Sci Date: 1986 Impact factor: 5.691

6. Radiolabelled uterine proteins during early pregnancy and pseudopregnancy in mice after unilateral ovariectomy and superovulation.

Authors: S B Fishel
Journal: J Reprod Fertil Date: 1980-07

7. Lectin-binding characteristics of mouse oviduct and uterus associated with pregnancy block by autologous antiprogesterone monoclonal antibody.

Authors: A Whyte; C Yang; F Rutter; R B Heap
Journal: J Reprod Immunol Date: 1987-07 Impact factor: 4.054

The effect of anti-prolactin antibody on in vitro synthesis of a pregnancy-associated rat uterine glycoprotein.

1. The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy.

2. The effect of ether and laparatomy on serum prolactin levels in progesterone-treated intact and ovariectomized rats.

3. Semicircadian rhythm in plasma levels of prolactin during early gestation in the rat.

4. Serum prolactin levels in rats during different reproductive states.

Review 5. Hormonal basis of maternal behavior in the rat.

6. Radiolabelled uterine proteins during early pregnancy and pseudopregnancy in mice after unilateral ovariectomy and superovulation.

7. Lectin-binding characteristics of mouse oviduct and uterus associated with pregnancy block by autologous antiprogesterone monoclonal antibody.

8. Ontogeny and implication of pregnancy-associated agglutinin of the rat uterus.

9. Carbohydrate-binding profile of a pregnancy-associated rat uterine glycoprotein.

10. Proteins synthesized by the rat endometrium during early pregnancy.

1. A mannose-binding glycoprotein found in the 4 day post coital rat uterus is involved in pregnancy.