| Literature DB >> 944951 |
O Greengard, M S Yoss, J A Del Valle.
Abstract
alpha-Methylphenylalanine reduces the phenylalanine hydroxylase activity of rat liver by 75 percent. Daily injections of this substance (plus phenylalanine) into rats from the 3rd to 15th day of age had no obvious toxic effects, and maintained a plasma concentration of phenylalanine comparable to that of phenylketonuric subjects.Entities:
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Year: 1976 PMID： 944951 DOI： 10.1126/science.944951
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728