Literature DB >> 9449286

Cloning and nucleotide sequence of the DNA gyrase gyrA gene from Serratia marcescens and characterization of mutations in gyrA of quinolone-resistant clinical isolates.

J H Kim1, E H Cho, K S Kim, H Y Kim, Y M Kim.   

Abstract

The sequence of the DNA gyrase gyrA gene of Serratia marcescens ATCC 14756 was determined. An open reading frame of 2,640 nucleotides coding for a polypeptide with a calculated molecular mass of 97,460 was found, and its sequence complemented the sequence of an Escherichia coli gyrA temperature-sensitive mutation. Analysis of the PCR products of the quinolone resistance-determining regions of gyrA genes from six quinolone-resistant clinical isolates revealed a single amino acid substitution, Ser-83 to Arg or Asp-87 to Tyr, in all six mutants, suggesting that a mutational alteration in gyrA is a common mechanism of quinolone resistance in S. marcescens.

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Year:  1998        PMID： 9449286      PMCID： PMC105481     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  44 in total

1.  gyrA mutations in quinolone-resistant isolates of the fish pathogen Aeromonas salmonicida.

Authors:  H Oppegaard; H Sørum
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

2.  Cloning and sequencing of the gyrA gene from the plant pathogen Erwinia carotovora.

Authors:  A Rosanas; J Barbé; I Gibert
Journal:  Gene       Date:  1995-08-08       Impact factor: 3.688

3.  Sequence of quinolone resistance-determining region of gyrA gene for clinical isolates and for an in vitro-selected quinolone-resistant strain of Coxiella burnetii.

Authors:  D Musso; M Drancourt; S Osscini; D Raoult
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191

4.  Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori.

Authors:  R A Moore; B Beckthold; S Wong; A Kureishi; L E Bryan
Journal:  Antimicrob Agents Chemother       Date:  1995-01       Impact factor: 5.191

5.  Incomplete cross-resistance of nalidixic and pipemidic acid-resistant variants of Serratia marcescens against ciprofloxacin, enoxacin, and norfloxacin.

Authors:  W H Traub
Journal:  Chemotherapy       Date:  1985       Impact factor: 2.544

6.  Association between double mutation in gyrA gene of ciprofloxacin-resistant clinical isolates of Escherichia coli and MICs.

Authors:  J Vila; J Ruiz; F Marco; A Barcelo; P Goñi; E Giralt; T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

7.  Cloning and nucleotide sequence of Pseudomonas aeruginosa DNA gyrase gyrA gene from strain PAO1 and quinolone-resistant clinical isolates.

Authors:  A Kureishi; J M Diver; B Beckthold; T Schollaardt; L E Bryan
Journal:  Antimicrob Agents Chemother       Date:  1994-09       Impact factor: 5.191

8.  Sequence analysis of the Rickettsia prowazekii gyrA gene.

Authors:  D O Wood; R T Waite
Journal:  Gene       Date:  1994-12-30       Impact factor: 3.688

9.  Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates.

Authors:  R J Belland; S G Morrison; C Ison; W M Huang
Journal:  Mol Microbiol       Date:  1994-10       Impact factor: 3.501

10.  Mutation in the gyrA gene of quinolone-resistant clinical isolates of Acinetobacter baumannii.

Authors:  J Vila; J Ruiz; P Goñi; A Marcos; T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1995-05       Impact factor: 5.191
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  12 in total

1.  Endocarditis caused by extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae: emergence of resistance to ciprofloxacin and piperacillin-tazobactam during treatment despite initial susceptibility.

Authors:  Oren Zimhony; Inna Chmelnitsky; Rita Bardenstein; Sorel Goland; Orly Hammer Muntz; Shiri Navon Venezia; Yehuda Carmeli
Journal:  Antimicrob Agents Chemother       Date:  2006-09       Impact factor: 5.191

2.  Identification of a Serratia marcescens clinical isolate with multiple quinolone resistance mechanisms from China.

Authors:  Hai-Fei Yang; Jun Cheng; Li-Fen Hu; Ying Ye; Jia-Bin Li
Journal:  Antimicrob Agents Chemother       Date:  2012-08-13       Impact factor: 5.191

3.  Novel combination of mutations in the DNA gyrase and topoisomerase IV genes in laboratory-grown fluoroquinolone-resistant Shigella flexneri mutants.

Authors:  Y W Chu; E T Houang; A F Cheng
Journal:  Antimicrob Agents Chemother       Date:  1998-11       Impact factor: 5.191

Review 4.  Mechanisms of fluoroquinolone resistance: an update 1994-1998.

Authors:  L J Piddock
Journal:  Drugs       Date:  1999       Impact factor: 9.546

5.  Effects of rice seed surface sterilization with hypochlorite on inoculated Burkholderia vietnamiensis.

Authors:  L Miché; J Balandreau
Journal:  Appl Environ Microbiol       Date:  2001-07       Impact factor: 4.792

Review 6.  Serratia infections: from military experiments to current practice.

Authors:  Steven D Mahlen
Journal:  Clin Microbiol Rev       Date:  2011-10       Impact factor: 26.132

7.  Comparison of agar dilution, disk diffusion, MicroScan, and Vitek antimicrobial susceptibility testing methods to broth microdilution for detection of fluoroquinolone-resistant isolates of the family Enterobacteriaceae.

Authors:  C D Steward; S A Stocker; J M Swenson; C M O'Hara; J R Edwards; R P Gaynes; J E McGowan; F C Tenover
Journal:  J Clin Microbiol       Date:  1999-03       Impact factor: 5.948

8.  Differential distribution of plasmid-mediated quinolone resistance genes in clinical enterobacteria with unusual phenotypes of quinolone susceptibility from Argentina.

Authors:  Patricia Andres; Celeste Lucero; Alfonso Soler-Bistué; Leonor Guerriero; Ezequiel Albornoz; Tung Tran; Angeles Zorreguieta; Marcelo Galas; Alejandra Corso; Marcelo E Tolmasky; Alejandro Petroni
Journal:  Antimicrob Agents Chemother       Date:  2013-03-11       Impact factor: 5.191

9.  Mutations in topoisomerase genes of fluoroquinolone-resistant salmonellae in Hong Kong.

Authors:  J M Ling; E W Chan; A W Lam; A F Cheng
Journal:  Antimicrob Agents Chemother       Date:  2003-11       Impact factor: 5.191

10.  Analysis of the gyrA gene of clinical Yersinia ruckeri isolates with reduced susceptibility to quinolones.

Authors:  Alicia Gibello; M Concepción Porrero; M Mar Blanco; Ana I Vela; Pilar Liébana; Miguel A Moreno; José F Fernández-Garayzábal; Lucas Domínguez
Journal:  Appl Environ Microbiol       Date:  2004-01       Impact factor: 4.792
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