Literature DB >> 9449281

In vitro activity of sanfetrinem and affinity for the penicillin-binding proteins of Streptococcus pneumoniae.

F Sifaoui1, E Varon, M D Kitzis, L Gutmann.   

Abstract

Against penicillin-susceptible pneumococci, the activity of sanfetrinem was similar to those of penicillin, amoxicillin, cefotaxime, imipenem, and meropenem, while against penicillin-resistant strains, sanfetrinem and the carbapenems exhibited superior activity (MICs at which 90% of strains are inhibited, < or =1 microg/ml). PBP 1a in the penicillin-susceptible strain and PBP 1a and PBP 2b in the more resistant isolates seemed to be the essential penicillin-binding proteins for imipenem and sanfetrinem.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9449281      PMCID： PMC105476          DOI： 10.1128/AAC.42.1.173

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Two bactericidal targets for penicillin in pneumococci: autolysis-dependent and autolysis-independent killing mechanisms.

Authors:  P Moreillon; Z Markiewicz; S Nachman; A Tomasz
Journal:  Antimicrob Agents Chemother       Date:  1990-01       Impact factor: 5.191

Review 2.  Penicillin-binding proteins and the antibacterial effectiveness of beta-lactam antibiotics.

Authors:  A Tomasz
Journal:  Rev Infect Dis       Date:  1986 Jul-Aug

3.  In vitro activity of the tribactam GV104326 against gram-positive, gram-negative, and anaerobic bacteria.

Authors:  E Di Modugno; I Erbetti; L Ferrari; G Galassi; S M Hammond; L Xerri
Journal:  Antimicrob Agents Chemother       Date:  1994-10       Impact factor: 5.191

4.  Inhibition of cell wall synthesis and acylation of the penicillin binding proteins during prolonged exposure of growing Streptococcus pneumoniae to benzylpenicillin.

Authors:  R Williamson; A Tomasz
Journal:  Eur J Biochem       Date:  1985-09-16

5.  MIC and time-kill studies of antipneumococcal activity of GV 118819X (sanfetrinem) compared with those of other agents.

Authors:  S K Spangler; M R Jacobs; P C Appelbaum
Journal:  Antimicrob Agents Chemother       Date:  1997-01       Impact factor: 5.191

6.  Penicillin tolerance in multiply drug-resistant natural isolates of Streptococcus pneumoniae.

Authors:  H H Liu; A Tomasz
Journal:  J Infect Dis       Date:  1985-08       Impact factor: 5.226

7.  In vivo interaction of beta-lactam antibiotics with the penicillin-binding proteins of Streptococcus pneumoniae.

Authors:  R Williamson; R Hakenbeck; A Tomasz
Journal:  Antimicrob Agents Chemother       Date:  1980-10       Impact factor: 5.191

8.  Interaction of non-lytic beta-lactams with penicillin-binding proteins in Streptococcus pneumoniae.

Authors:  R Hakenbeck; S Tornette; N F Adkinson
Journal:  J Gen Microbiol       Date:  1987-03

Review 9.  Management of infections caused by antibiotic-resistant Streptococcus pneumoniae.

Authors:  I R Friedland; G H McCracken
Journal:  N Engl J Med       Date:  1994-08-11       Impact factor: 91.245

10.  Penicillin resistance and defective lysis in clinical isolates of pneumococci: evidence for two kinds of antibiotic pressure operating in the clinical environment.

Authors:  P Moreillon; A Tomasz
Journal:  J Infect Dis       Date:  1988-06       Impact factor: 5.226
View more
  2 in total

Review 1.  Emerging strategies in infectious diseases: new carbapenem and trinem antibacterial agents.

Authors:  H S Sader; A C Gales
Journal:  Drugs       Date:  2001       Impact factor: 9.546

2.  Effects of amino acid alterations in penicillin-binding proteins (PBPs) 1a, 2b, and 2x on PBP affinities of penicillin, ampicillin, amoxicillin, cefditoren, cefuroxime, cefprozil, and cefaclor in 18 clinical isolates of penicillin-susceptible, -intermediate, and -resistant pneumococci.

Authors:  Kensuke Nagai; Todd A Davies; Michael R Jacobs; Peter C Appelbaum
Journal:  Antimicrob Agents Chemother       Date:  2002-05       Impact factor: 5.191
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.