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23 in total

Review 1. Accelerating cocaine metabolism as an approach to the treatment of cocaine abuse and toxicity.

Authors: Charles W Schindler; Steven R Goldberg
Journal: Future Med Chem Date: 2012-02 Impact factor: 3.808

2. Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation.

Authors: Daquan Gao; Hoon Cho; Wenchao Yang; Yongmei Pan; Guangfu Yang; Hsin-Hsiung Tai; Chang-Guo Zhan
Journal: Angew Chem Int Ed Engl Date: 2006-01-16 Impact factor: 15.336

3. First-principles calculation of pKa for cocaine, nicotine, neurotransmitters, and anilines in aqueous solution.

Authors: Haiting Lu; Xi Chen; Chang-Guo Zhan
Journal: J Phys Chem B Date: 2007-08-11 Impact factor: 2.991

4. Cocaine esterase-cocaine binding process and the free energy profiles by molecular dynamics and potential of mean force simulations.

Authors: Xiaoqin Huang; Xinyun Zhao; Fang Zheng; Chang-Guo Zhan
Journal: J Phys Chem B Date: 2012-03-02 Impact factor: 2.991

5. Reaction mechanism for cocaine esterase-catalyzed hydrolyses of (+)- and (-)-cocaine: unexpected common rate-determining step.

Authors: Junjun Liu; Xinyun Zhao; Wenchao Yang; Chang-Guo Zhan
Journal: J Phys Chem B Date: 2011-04-12 Impact factor: 2.991

Peripheral cocaine-blocking agents: new medications for cocaine dependence. An introduction to immunological and enzymatic approaches to treating cocaine dependence reported by Fox, Gorelick and Cohen in the immediately succeeding articles (see pages 153-174).

Review 1. Accelerating cocaine metabolism as an approach to the treatment of cocaine abuse and toxicity.

2. Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation.

3. First-principles calculation of pKa for cocaine, nicotine, neurotransmitters, and anilines in aqueous solution.

4. Cocaine esterase-cocaine binding process and the free energy profiles by molecular dynamics and potential of mean force simulations.

5. Reaction mechanism for cocaine esterase-catalyzed hydrolyses of (+)- and (-)-cocaine: unexpected common rate-determining step.

6. Computational redesign of human butyrylcholinesterase for anticocaine medication.

Review 7. Rational design of an enzyme mutant for anti-cocaine therapeutics.

8. Reaction Pathway and Free Energy Profile for Cocaine Hydrolase-Catalyzed Hydrolysis of (-)-Cocaine.

9. Mechanism for cocaine blocking the transport of dopamine: insights from molecular modeling and dynamics simulations.

Review 10. Structure-and-mechanism-based design and discovery of therapeutics for cocaine overdose and addiction.