Literature DB >> 944449

Effects of chlorpromazine on avoidance and escape responding in humans.

M W Fischman, R C Smith, C R Schuster.   

Abstract

The effects of chlorpromazine on shock avoidance and escape responding were determined using four human subjects lever pressing on a modified free operant avoidance schedule. Doses of chlorpromazine ranging from 50 to 100 mg and shock levels ranging from 0.35 to 3.0 mA were used. In general, the results showed that chlorpromazine suppressed avoidance responding at doses which did not suppress escape responding.

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Year:  1976        PMID: 944449     DOI: 10.1016/0091-3057(76)90184-2

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN: 0091-3057            Impact factor:   3.533


  5 in total

1.  Probabilistic classification and gambling in patients with schizophrenia receiving medication: comparison of risperidone, olanzapine, clozapine and typical antipsychotics.

Authors:  James I Wasserman; Rebecca J Barry; Lisa Bradford; Nicholas J Delva; Richard J Beninger
Journal:  Psychopharmacology (Berl)       Date:  2012-01-12       Impact factor: 4.530

Review 2.  Regional differences in the action of antipsychotic drugs: implications for cognitive effects in schizophrenic patients.

Authors:  Richard J Beninger; Tyson W Baker; Matthew M Florczynski; Tomek J Banasikowski
Journal:  Neurotox Res       Date:  2010-04-08       Impact factor: 3.911

3.  A single dose study of nabilone, a synthetic cannabinoid.

Authors:  R M Glass; E H Uhlenhuth; F W Hartel; C R Schuster; M W Fischman
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

Review 4.  Dopamine and incentive learning: a framework for considering antipsychotic medication effects.

Authors:  Richard J Beninger
Journal:  Neurotox Res       Date:  2006-12       Impact factor: 3.911

5.  The effects of chlorpromazine and pentobarbital on behavior maintained by electric shock or point loss avoidance in humans.

Authors:  M W Fischman; C R Schuster
Journal:  Psychopharmacology (Berl)       Date:  1979       Impact factor: 4.530

  5 in total

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