Literature DB >> 9442869

Microtubule polymerization dynamics.

A Desai1, T J Mitchison.   

Abstract

The polymerization dynamics of microtubules are central to their biological functions. Polymerization dynamics allow microtubules to adopt spatial arrangements that can change rapidly in response to cellular needs and, in some cases, to perform mechanical work. Microtubules utilize the energy of GTP hydrolysis to fuel a unique polymerization mechanism termed dynamic instability. In this review, we first describe progress toward understanding the mechanism of dynamic instability of pure tubulin and then discuss the function and regulation of microtubule dynamic instability in living cells.

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Year:  1997        PMID： 9442869     DOI： 10.1146/annurev.cellbio.13.1.83

Source DB:  PubMed          Journal:  Annu Rev Cell Dev Biol        ISSN： 1081-0706            Impact factor:   13.827


  783 in total

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Journal:  J Cell Biol       Date:  1999-09-20       Impact factor: 10.539

3.  Force-velocity relation for growing microtubules.

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4.  The TACC domain identifies a family of centrosomal proteins that can interact with microtubules.

Authors:  F Gergely; C Karlsson; I Still; J Cowell; J Kilmartin; J W Raff
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

5.  Cell cycle-dependent changes in microtubule dynamics in living cells expressing green fluorescent protein-alpha tubulin.

Authors:  N M Rusan; C J Fagerstrom; A M Yvon; P Wadsworth
Journal:  Mol Biol Cell       Date:  2001-04       Impact factor: 4.138

6.  Protein phosphatase 2A is associated in an inactive state with microtubules through 2A1-specific interaction with tubulin.

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Journal:  Biochem J       Date:  2000-03-01       Impact factor: 3.857

7.  ZipA is a MAP-Tau homolog and is essential for structural integrity of the cytokinetic FtsZ ring during bacterial cell division.

Authors:  D RayChaudhuri
Journal:  EMBO J       Date:  1999-05-04       Impact factor: 11.598

8.  Feedback interactions between cell-cell adherens junctions and cytoskeletal dynamics in newt lung epithelial cells.

Authors:  C M Waterman-Storer; W C Salmon; E D Salmon
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9.  Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast.

Authors:  K A Kosco; C G Pearson; P S Maddox; P J Wang; I R Adams; E D Salmon; K Bloom; T C Huffaker
Journal:  Mol Biol Cell       Date:  2001-09       Impact factor: 4.138

10.  Antagonistic forces generated by myosin II and cytoplasmic dynein regulate microtubule turnover, movement, and organization in interphase cells.

Authors:  A M Yvon; D J Gross; P Wadsworth
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-03       Impact factor: 11.205
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