| Literature DB >> 9440031 |
S L Pomeroy1, M E Sutton, L C Goumnerova, R A Segal.
Abstract
Medulloblastomas may be derived from granule cells of the developing cerebellum. Children with tumors expressing high levels of the neurotrophin-3 receptor, TrkC, have a more favorable outcome. During development, TrkC is expressed in the most mature granule cells. Favorable medulloblastomas may be derived from more highly differentiated granule cells.Entities:
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Year: 1997 PMID: 9440031 DOI: 10.1023/a:1005841206252
Source DB: PubMed Journal: J Neurooncol ISSN: 0167-594X Impact factor: 4.130