Literature DB >> 9440026

Platelet-derived growth factor in human brain tumors.

M Kirsch1, J C Wilson, P Black.   

Abstract

This paper initially reviews ligand and receptor systems for the PDGF family and the signalling systems they use as well as their role in neural developments. It then describes the putative role of this family in astrocytoma, meningioma, and pituitary adenoma pathogenesis. Potential therapies with receptor antagonists or dominant negative mutants are discussed in the final sections.

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Year:  1997        PMID： 9440026     DOI： 10.1023/a:1005872718547

Source DB:  PubMed          Journal:  J Neurooncol        ISSN： 0167-594X            Impact factor:   4.130


  96 in total

Review 1.  Growth factors in development, transformation, and tumorigenesis.

Authors:  M Cross; T M Dexter
Journal:  Cell       Date:  1991-01-25       Impact factor: 41.582

2.  Antiproliferative effect of trapidil on PDGF-associated growth of human glioma cell lines in vitro.

Authors:  M Tada; T Aida; M Hosokawa; H Kobayashi; Y Sawamura; H Abe
Journal:  Neurol Med Chir (Tokyo)       Date:  1991-06       Impact factor: 1.742

3.  Correlation of glial proliferation with age in the mouse brain.

Authors:  M M Dalton; O R Hommes; C P Leblond
Journal:  J Comp Neurol       Date:  1968-12       Impact factor: 3.215

Review 4.  The molecular basis of oncogenes and tumor suppressor genes.

Authors:  R A Weinberg
Journal:  Ann N Y Acad Sci       Date:  1995-06-30       Impact factor: 5.691

5.  Proliferation of different cell types in the brain.

Authors:  H Korr
Journal:  Adv Anat Embryol Cell Biol       Date:  1980       Impact factor: 1.231

6.  Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors.

Authors:  D Anderson; C A Koch; L Grey; C Ellis; M F Moran; T Pawson
Journal:  Science       Date:  1990-11-16       Impact factor: 47.728

7.  Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation.

Authors:  M Hermansson; M Nistér; C Betsholtz; C H Heldin; B Westermark; K Funa
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

8.  Cyclic AMP blocks expression of the c-sis gene in tumor cells.

Authors:  G R Harsh; W M Kavanaugh; N F Starksen; L T Williams
Journal:  Oncogene Res       Date:  1989

9.  Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells.

Authors:  S M Shamah; C D Stiles; A Guha
Journal:  Mol Cell Biol       Date:  1993-12       Impact factor: 4.272

10.  PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage.

Authors:  N P Pringle; H S Mudhar; E J Collarini; W D Richardson
Journal:  Development       Date:  1992-06       Impact factor: 6.868
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  4 in total

Review 1.  Medical therapies for meningiomas.

Authors:  Patrick Y Wen; Eudocia Quant; Jan Drappatz; Rameen Beroukhim; Andrew D Norden
Journal:  J Neurooncol       Date:  2010-09-04       Impact factor: 4.130

Review 2.  Genetics of brain neoplasms.

Authors:  J R Shapiro
Journal:  Curr Neurol Neurosci Rep       Date:  2001-05       Impact factor: 5.081

3.  Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08).

Authors:  Patrick Y Wen; W K Alfred Yung; Kathleen R Lamborn; Andrew D Norden; Timothy F Cloughesy; Lauren E Abrey; Howard A Fine; Susan M Chang; H Ian Robins; Karen Fink; Lisa M Deangelis; Minesh Mehta; Emmanuelle Di Tomaso; Jan Drappatz; Santosh Kesari; Keith L Ligon; Ken Aldape; Rakesh K Jain; Charles D Stiles; Merrill J Egorin; Michael D Prados
Journal:  Neuro Oncol       Date:  2009-12       Impact factor: 12.300

4.  Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment.

Authors:  Ping Guo; Bo Hu; Weisong Gu; Li Xu; Degui Wang; Hui-Jen Su Huang; Webster K Cavenee; Shi-Yuan Cheng
Journal:  Am J Pathol       Date:  2003-04       Impact factor: 4.307
  4 in total

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