Literature DB >> 943947

Placental transfer of clindamycin and gentamicin in term pregnancy.

A J Weinstein, R S Gibbs, M Gallagher.   

Abstract

The pharmacokinetics of clindamycin and gentamicin were studied in women given these antibiotics prior to cesarean section. Maternal clindamycin levels were within the normal range and cord levels were within the therapeutic range for this antibiotic. For gentamicin, however, maternal levels were depressed, with a concurrent depression of cord levels. This may have significant implications for the use of gentamicin in maternal and fetomaternal infections.

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Year:  1976        PMID: 943947     DOI: 10.1016/s0002-9378(16)33336-1

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  12 in total

1.  [Acne therapy in pregnancy].

Authors:  C Bayerl
Journal:  Hautarzt       Date:  2013-04       Impact factor: 0.751

2.  Transplacental passage of clindamycin from mother to neonate.

Authors:  C D Wear; C V Towers; M S Brown; B Weitz; S Porter; L Wolfe
Journal:  J Perinatol       Date:  2016-08-04       Impact factor: 2.521

Review 3.  Drug kinetics in childbirth.

Authors:  R L Nation
Journal:  Clin Pharmacokinet       Date:  1980 Jul-Aug       Impact factor: 6.447

4.  Drug-induced ototoxicity.

Authors:  R E Brummett
Journal:  Drugs       Date:  1980-06       Impact factor: 9.546

Review 5.  Effects of antibacterials on the unborn child: what is known and how should this influence prescribing.

Authors:  A Einarson; S Shuhaiber; G Koren
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

6.  Pharmacokinetics of clindamycin in pregnant women in the peripartum period.

Authors:  Anouk E Muller; Johan W Mouton; Paul M Oostvogel; P Joep Dörr; Rob A Voskuyl; Joost DeJongh; Eric A P Steegers; Meindert Danhof
Journal:  Antimicrob Agents Chemother       Date:  2010-02-22       Impact factor: 5.191

7.  The Role of Megalin in the Transport of Gentamicin Across BeWo Cells, an In Vitro Model of the Human Placenta.

Authors:  Amal A Akour; Mary Jayne Kennedy; Phillip M Gerk
Journal:  AAPS J       Date:  2015-05-19       Impact factor: 4.009

Review 8.  Drugs for the Prevention and Treatment of Sepsis in the Newborn.

Authors:  Sagori Mukhopadhyay; Kelly C Wade; Karen M Puopolo
Journal:  Clin Perinatol       Date:  2019-03-30       Impact factor: 3.430

Review 9.  Pharmacokinetics of antibiotics in pregnancy and labour.

Authors:  A Philipson
Journal:  Clin Pharmacokinet       Date:  1979 Jul-Aug       Impact factor: 6.447

10.  Ceftriaxone distribution between maternal blood and fetal blood and tissues at parturition and between blood and milk postpartum.

Authors:  D A Kafetzis; D C Brater; J E Fanourgakis; J Voyatzis; P Georgakopoulos
Journal:  Antimicrob Agents Chemother       Date:  1983-06       Impact factor: 5.191

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