Literature DB >> 9438838

Kinesin and dynein superfamily proteins and the mechanism of organelle transport.

N Hirokawa1.   

Abstract

Cells transport and sort proteins and lipids, after their synthesis, to various destinations at appropriate velocities in membranous organelles and protein complexes. Intracellular transport is thus fundamental to cellular morphogenesis and functioning. Microtubules serve as a rail on which motor proteins, such as kinesin and dynein superfamily proteins, convey their cargoes. This review focuses on the molecular mechanism of organelle transport in cells and describes kinesin and dynein superfamily proteins.

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Year:  1998        PMID： 9438838     DOI： 10.1126/science.279.5350.519

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  445 in total

1.  Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3.

Authors:  Z Yang; Ch Xia; E A Roberts; K Bush; S K Nigam; L S Goldstein
Journal:  Mol Cell Biol       Date:  2001-02       Impact factor: 4.272

2.  Functional analysis of mouse C-terminal kinesin motor KifC2.

Authors:  Z Yang; E A Roberts; L S Goldstein
Journal:  Mol Cell Biol       Date:  2001-04       Impact factor: 4.272

Review 3.  Selective targeting of glutamate receptors in neurons.

Authors:  M E Rubio
Journal:  Mol Neurobiol       Date:  2000 Feb-Apr       Impact factor: 5.590

4.  Increased protein phosphorylation of cytoplasmic dynein results in impaired motor function.

Authors:  M T Runnegar; X Wei; S F Hamm-Alvarez
Journal:  Biochem J       Date:  1999-08-15       Impact factor: 3.857

5.  Functional dissection and hierarchy of tubulin-folding cofactor homologues in fission yeast.

Authors:  P A Radcliffe; D Hirata; L Vardy; T Toda
Journal:  Mol Biol Cell       Date:  1999-09       Impact factor: 4.138

6.  Differential distribution of intracellular glutamate receptors in dendrites.

Authors:  M E Rubio; R J Wenthold
Journal:  J Neurosci       Date:  1999-07-01       Impact factor: 6.167

7.  Direct inhibition of microtubule-based kinesin motility by local anesthetics.

Authors:  Y Miyamoto; E Muto; T Mashimo; A H Iwane; I Yoshiya; T Yanagida
Journal:  Biophys J       Date:  2000-02       Impact factor: 4.033

8.  Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons.

Authors:  C Kaether; P Skehel; C G Dotti
Journal:  Mol Biol Cell       Date:  2000-04       Impact factor: 4.138

9.  The kinesin-like calmodulin binding protein is differentially involved in cell division.

Authors:  J W Vos; F Safadi; A S Reddy; P K Hepler
Journal:  Plant Cell       Date:  2000-06       Impact factor: 11.277

Review 10.  Searching for kinesin's mechanical amplifier.

Authors:  R D Vale; R Case; E Sablin; C Hart; R Fletterick
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2000-04-29       Impact factor: 6.237
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