Genetic markers and acute febrile urinary tract infection in the 1st year of life.

Blood groups ABO, MN, Rhesus, P, and Lewis, salivary ABH secretion, and at the HLA DQ alpha locus were studied in 65 Caucasian children of both sexes diagnosed as having acute febrile urinary tract infection in the 1st year of life, as well as in 60 Caucasian control children. No differences were observed between patients and controls. Results from patients with normal urinary tracts were also similar to those from patients with primary vesicoureteral reflux. We could not confirm previous findings suggesting different susceptibility to urinary tract infection based on phenotypes of several genetic markers.