Literature DB >> 9438129

PDGF- and TGF-beta-induced changes in cell shape of invertebrate immunocytes: effect of calcium entry blockers.

E Ottaviani1, D Sassi, D Kletsas.   

Abstract

The cellular activity of hemocytes from the marine mollusc Mytilus galloprovincialis was studied using computer-assisted microscopic image analysis. PDGF-AB and TGF-beta 1 caused changes in cellular shape and induced the immunocytes to migrate in a chemotactic manner. The effect of PDGF-AB was more potent than that of TGF-beta 1, and the responses were dose-correlated for PDGF-AB, while they were dose-dependent up to 5 pg/ml for TGF-beta 1. Moreover, the PDGF-AB response was extracellular Ca(2+)-independent, while TGF-beta 1 was Ca(2+)-dependent.

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Year:  1997        PMID： 9438129

Source DB:  PubMed          Journal:  Eur J Cell Biol        ISSN： 0171-9335            Impact factor:   4.492


  4 in total

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Authors:  Jonathan H Schultz; Coen M Adema
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Review 3.  Immune-Neuroendocrine Interactions: Evolution, Ecology, and Susceptibility to Illness.

Authors:  Johanna M C Blom; Enzo Ottaviani
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4.  Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity.

Authors:  Shirley Luckhart; Andrea L Crampton; Ruben Zamora; Matthew J Lieber; Patricia C Dos Santos; Tina M L Peterson; Nicole Emmith; Junghwa Lim; David A Wink; Yoram Vodovotz
Journal:  Infect Immun       Date:  2003-06       Impact factor: 3.441
  4 in total

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