Literature DB >> 9435889

Neuronal nicotinic acetylcholine receptors as targets for drug discovery.

M W Holladay1, M J Dart, J K Lynch.   

Abstract

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Year:  1997        PMID： 9435889     DOI： 10.1021/jm970377o

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  47 in total

1.  An improved nicotinic pharmacophore and a stereoselective CoMFA-model for nicotinic agonists acting at the central nicotinic acetylcholine receptors labelled by.

Authors:  J E Tønder; P H Olesen; J B Hansen; M Begtrup; I Pettersson
Journal:  J Comput Aided Mol Des       Date:  2001-03       Impact factor: 3.686

2.  Neuronal nicotinic receptor agonists: a multi-approach development of the pharmacophore.

Authors:  O Nicolotti; M Pellegrini-Calace; A Carrieri; C Altomare; N B Centeno; F Sanz; A Carotti
Journal:  J Comput Aided Mol Des       Date:  2001-09       Impact factor: 3.686

3.  N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors.

Authors:  Jianhong Chen; Seth Norrholm; Linda P Dwoskin; Peter A Crooks; Donglu Bai
Journal:  Bioorg Med Chem Lett       Date:  2003-01-06       Impact factor: 2.823

4.  Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.

Authors:  Sheela K Chellappan; Yingxian Xiao; Werner Tueckmantel; Kenneth J Kellar; Alan P Kozikowski
Journal:  J Med Chem       Date:  2006-05-04       Impact factor: 7.446

5.  Mechanisms of efferent-mediated responses in the turtle posterior crista.

Authors:  Joseph C Holt; Anna Lysakowski; Jay M Goldberg
Journal:  J Neurosci       Date:  2006-12-20       Impact factor: 6.167

6.  TC-2559 excites dopaminergic neurones in the ventral tegmental area by stimulating alpha4beta2-like nicotinic acetylcholine receptors in anaesthetised rats.

Authors:  Yun Wang; John L Sherwood; Colin P Miles; Gary Whiffin; David Lodge
Journal:  Br J Pharmacol       Date:  2006-02       Impact factor: 8.739

7.  Non-competitive inhibitory activities of morphinan and morphine derivatives at the alpha 3 beta 4 Neuronal nicotinic acetylcholine receptor determined using nonlinear chromatography and chemometric techniques.

Authors:  Krzysztof Jozwiak; Ruin Moaddel; Rika Yamaguchi; Alexandre Maciuk; Irving W Wainer
Journal:  Pharm Res       Date:  2006-08-09       Impact factor: 4.200

8.  Improvement of contextual memory by S 24795 in aged mice: comparison with memantine.

Authors:  Daniel Beracochea; Aurelie Boucard; Caryn Trocme-Thibierge; Philippe Morain
Journal:  Psychopharmacology (Berl)       Date:  2007-11-22       Impact factor: 4.530

Review 9.  Nicotinic agonists, antagonists, and modulators from natural sources.

Authors:  John W Daly
Journal:  Cell Mol Neurobiol       Date:  2005-06       Impact factor: 5.046

10.  Higher susceptibility to halothane modulation in open- than in closed-channel alpha4beta2 nAChR revealed by molecular dynamics simulations.

Authors:  Lu Tian Liu; Esmael J Haddadian; Dan Willenbring; Yan Xu; Pei Tang
Journal:  J Phys Chem B       Date:  2010-01-14       Impact factor: 2.991
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