Literature DB >> 9434945

Complete sequence and polymorphism study of the human TYRP1 gene encoding tyrosinase-related protein 1.

N F Box1, J R Wyeth, C J Mayne, L E O'Gorman, N G Martin, R A Sturm.   

Abstract

The complete 24,667 nucleotide sequence spanning the human TYRP1 gene has been determined from the inserts of two overlapping lambda clones. A LINE-1 repeat element is immediately adjacent to and may demarcate the immediate 5' promoter region of the gene. A search for polymorphism within the seven TYRP1 coding exons has been performed by an RNase mismatch detection procedure. Analysis of the TYRP1 gene in 100 Caucasian individuals of varying hair color has found no amino acid sequence variation nor revealed any hemizygous mutant allele in the hypopigmented phenotype of two 9p- syndrome patients.

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Year:  1998        PMID： 9434945     DOI： 10.1007/s003359900678

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  32 in total

1.  Assignment of the human TYRP (brown) locus to chromosome region 9p23 by nonradioactive in situ hybridization.

Authors:  V V Murty; B Bouchard; S Mathew; S Vijayasaradhi; A N Houghton
Journal:  Genomics       Date:  1992-05       Impact factor: 5.736

2.  A high-resolution map of the brown (b, Tyrp1) deletion complex of mouse chromosome 4.

Authors:  J A Bell; E M Rinchik; S Raymond; R Suffolk; I J Jackson
Journal:  Mamm Genome       Date:  1995-06       Impact factor: 2.957

3.  Subfamily structure and evolution of the human L1 family of repetitive sequences.

Authors:  J Jurka
Journal:  J Mol Evol       Date:  1989-12       Impact factor: 2.395

4.  Dinucleotide repeat polymorphism at the human TYRP1 locus.

Authors:  N F Box; R A Sturm
Journal:  Hum Mol Genet       Date:  1994-12       Impact factor: 6.150

5.  Fibroblasts co-expressing tyrosinase and the b-protein synthesize both eumelanin and phaeomelanin.

Authors:  A J Winder; G Odh; E Rosengren; H Rorsman
Journal:  Biochim Biophys Acta       Date:  1995-09-21

6.  The tyrosinase-related protein-1 gene has a structure and promoter sequence very different from tyrosinase.

Authors:  I J Jackson; D M Chambers; P S Budd; R Johnson
Journal:  Nucleic Acids Res       Date:  1991-07-25       Impact factor: 16.971

Review 7.  Tyrosinase and related proteins in mammalian pigmentation.

Authors:  V del Marmol; F Beermann
Journal:  FEBS Lett       Date:  1996-03-04       Impact factor: 4.124

8.  Low nucleotide diversity in man.

Authors:  W H Li; L A Sadler
Journal:  Genetics       Date:  1991-10       Impact factor: 4.562

9.  Detection of a Tsp509I polymorphism in the 3' UTR of the human tyrosinase related protein-1 (TYRP) gene.

Authors:  S C Wildenberg; R A King; W S Oetting
Journal:  Hum Genet       Date:  1995-02       Impact factor: 4.132

10.  The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts.

Authors:  A J Winder; A Wittbjer; E Rosengren; H Rorsman
Journal:  J Cell Sci       Date:  1993-09       Impact factor: 5.285
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Authors:  Andrzej Slominski; Michal A Zmijewski; John Pawelek
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Review 2.  Tyrosinase related protein 1 (TYRP1/gp75) in human cutaneous melanoma.

Authors:  Ghanem Ghanem; Journé Fabrice
Journal:  Mol Oncol       Date:  2011-02-03       Impact factor: 6.603

3.  Genetic and in silico comparative mapping of the polyphenol oxidase gene in bread wheat (Triticum aestivum L.).

Authors:  Rosy Raman; Harsh Raman; Katie Johnstone; Chris Lisle; Alison Smith; Peter Martin; Peter Matin; Helen Allen
Journal:  Funct Integr Genomics       Date:  2005-05-26       Impact factor: 3.410

4.  Thymic expression of peripheral tissue antigens in humans: a remarkable variability among individuals.

Authors:  Hiroshi Takase; Cheng-Rong Yu; Rashid M Mahdi; Daniel C Douek; Gregory B Dirusso; Frank M Midgley; Rajpreet Dogra; Gloria Allende; Eliot Rosenkranz; Alberto Pugliese; Charles E Egwuagu; Igal Gery
Journal:  Int Immunol       Date:  2005-07-19       Impact factor: 4.823

5.  In situ quantification of individual mRNA transcripts in melanocytes discloses gene regulation of relevance to speciation.

Authors:  Chi-Chih Wu; Axel Klaesson; Julia Buskas; Petter Ranefall; Reza Mirzazadeh; Ola Söderberg; Jochen B W Wolf
Journal:  J Exp Biol       Date:  2019-03-08       Impact factor: 3.312

Review 6.  Oculocutaneous albinism.

Authors:  Karen Grønskov; Jakob Ek; Karen Brondum-Nielsen
Journal:  Orphanet J Rare Dis       Date:  2007-11-02       Impact factor: 4.123

7.  In silico screening and molecular dynamics simulation of disease-associated nsSNP in TYRP1 gene and its structural consequences in OCA3.

Authors:  Balu Kamaraj; Rituraj Purohit
Journal:  Biomed Res Int       Date:  2013-06-19       Impact factor: 3.411

Review 8.  Mutational analysis of oculocutaneous albinism: a compact review.

Authors:  Balu Kamaraj; Rituraj Purohit
Journal:  Biomed Res Int       Date:  2014-06-29       Impact factor: 3.411
  8 in total

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