Literature DB >> 9434787

Opposing actions of BMP3 and TGF beta 1 in human bone marrow stromal cell growth and differentiation.

C Faucheux1, F Ulysse, R Bareille, A H Reddi, J Amédée.   

Abstract

BMP3 and TGF beta 1 were found to induce opposite effects on human bone marrow stromal cells both in cell proliferation and cell differentiation and on calcium deposition onto the extracellular matrix. Moreover, BMP3 may exert, in part, the inhibitory effect of TGF beta 1 through decreasing the affinity of TGF-beta for its receptors which are now identified in these human bone cells.

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Year:  1997        PMID： 9434787     DOI： 10.1006/bbrc.1997.7792

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  4 in total

Review 1.  Agonists and Antagonists of TGF-β Family Ligands.

Authors:  Chenbei Chang
Journal:  Cold Spring Harb Perspect Biol       Date:  2016-08-01       Impact factor: 10.005

Review 2.  Pathophysiology and Emerging Molecular Therapeutic Targets in Heterotopic Ossification.

Authors:  Favour Felix-Ilemhenbhio; George A E Pickering; Endre Kiss-Toth; Jeremy Mark Wilkinson
Journal:  Int J Mol Sci       Date:  2022-06-23       Impact factor: 6.208

3.  Regulation of BMP-induced transcription in cultured human bone marrow stromal cells.

Authors:  David L Diefenderfer; Anna M Osyczka; Jonathan P Garino; Phoebe S Leboy
Journal:  J Bone Joint Surg Am       Date:  2003       Impact factor: 5.284

4.  Interaction of TGFβ and BMP signaling pathways during chondrogenesis.

Authors:  Bettina Keller; Tao Yang; Yuqing Chen; Elda Munivez; Terry Bertin; Bernhard Zabel; Brendan Lee
Journal:  PLoS One       Date:  2011-01-28       Impact factor: 3.240
  4 in total

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