Literature DB >> 9433635

Genomic sharing surrounding alleles identical by descent: effects of genetic drift and population growth.

G J te Meerman1, M A Van der Meulen.   

Abstract

The number of identical deleterious mutations present in a population may become very large, depending on the combined effect of genetic drift, population growth and limited negative selection. The distribution of the length of the shared area between two random chromosomes carrying the mutations has been investigated for a number of generations varying from 20-100 since introduction. The consequences for investigations using association and haplotype sharing methods are discussed.

Mesh：

Year:  1997        PMID： 9433635     DOI： 10.1002/(SICI)1098-2272(1997)14:6<1125::AID-GEPI94>3.0.CO;2-I

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN： 0741-0395            Impact factor:   2.135


  10 in total

1.  Haplotype-sharing analysis for alcohol dependence based on quantitative traits and the Mantel statistic.

Authors:  Andre Kleensang; Daniel Franke; Inke R König; Andreas Ziegler
Journal:  BMC Genet       Date:  2005-12-30       Impact factor: 2.797

2.  Shared genomic segment analysis. Mapping disease predisposition genes in extended pedigrees using SNP genotype assays.

Authors:  A Thomas; N J Camp; J M Farnham; K Allen-Brady; L A Cannon-Albright
Journal:  Ann Hum Genet       Date:  2007-12-18       Impact factor: 1.670

3.  A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics.

Authors:  Ida Moltke; Anders Albrechtsen; Thomas V O Hansen; Finn C Nielsen; Rasmus Nielsen
Journal:  Genome Res       Date:  2011-04-14       Impact factor: 9.043

4.  A Bayesian approach using covariance of single nucleotide polymorphism data to detect differences in linkage disequilibrium patterns between groups of individuals.

Authors:  Taane G Clark; Susana G Campino; Elisa Anastasi; Sarah Auburn; Yik Y Teo; Kerrin Small; Kirk A Rockett; Dominic P Kwiatkowski; Christopher C Holmes
Journal:  Bioinformatics       Date:  2010-06-16       Impact factor: 6.937

5.  Assessment of SNP streak statistics using gene drop simulation with linkage disequilibrium.

Authors:  Alun Thomas
Journal:  Genet Epidemiol       Date:  2010-02       Impact factor: 2.135

6.  A Dutch Fanconi Anemia FANCC Founder Mutation in Canadian Manitoba Mennonites.

Authors:  Yne de Vries; Nikki Lwiwski; Marieke Levitus; Bertus Kuyt; Sara J Israels; Fré Arwert; Michel Zwaan; Cheryl R Greenberg; Blanche P Alter; Hans Joenje; Hanne Meijers-Heijboer
Journal:  Anemia       Date:  2012-06-04

7.  Testing for association based on excess allele sharing in a sample of related cases and controls.

Authors:  Lambertus Klei; Kathyrn Roeder
Journal:  Hum Genet       Date:  2007-03-07       Impact factor: 5.881

8.  Splice-site mutations in the axonemal outer dynein arm docking complex gene CCDC114 cause primary ciliary dyskinesia.

Authors:  Alexandros Onoufriadis; Tamara Paff; Dinu Antony; Amelia Shoemark; Dimitra Micha; Bertus Kuyt; Miriam Schmidts; Stavroula Petridi; Jeanette E Dankert-Roelse; Eric G Haarman; Johannes M A Daniels; Richard D Emes; Robert Wilson; Claire Hogg; Peter J Scambler; Eddie M K Chung; Gerard Pals; Hannah M Mitchison
Journal:  Am J Hum Genet       Date:  2012-12-20       Impact factor: 11.025

9.  Estimating genealogies from linked marker data: a Bayesian approach.

Authors:  Dario Gasbarra; Matti Pirinen; Mikko J Sillanpää; Elja Arjas
Journal:  BMC Bioinformatics       Date:  2007-10-25       Impact factor: 3.169

10.  Association testing by haplotype-sharing methods applicable to whole-genome analysis.

Authors:  Ilja M Nolte; André R de Vries; Geert T Spijker; Ritsert C Jansen; Dumitru Brinza; Alexander Zelikovsky; Gerard J Te Meerman
Journal:  BMC Proc       Date:  2007-12-18
  10 in total

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