Literature DB >> 9433632

Affected sib-pair tests for linkage: type I errors with dependent sib-pairs.

F Meunier1, A Philippi, M Martinez, F Demenais.   

Abstract

We compared the robustness of affected-sib-pair (ASP) tests for multiple-affected sibships. Forming all possible pairs increases the type I errors only slightly whereas the most used weighting procedures decrease the efficiency of the tests. Another weighting procedure accounting for the reduction of variance of the weighted identical by descent (IBD) information appears robust. Missing parental marker data leads to a decrease of type I errors in all cases.

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Year:  1997        PMID： 9433632     DOI： 10.1002/(SICI)1098-2272(1997)14:6<1107::AID-GEPI91>3.0.CO;2-K

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN： 0741-0395            Impact factor:   2.135


  7 in total

1.  Multilocus linkage tests based on affected relative pairs.

Authors:  H J Cordell; G C Wedig; K B Jacobs; R C Elston
Journal:  Am J Hum Genet       Date:  2000-03-21       Impact factor: 11.025

2.  Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease.

Authors:  M Martinez; A Brice; J R Vaughan; A Zimprich; M M B Breteler; G Meco; A Filla; M J Farrer; C Bétard; J Hardy; G De Michele; V Bonifati; B Oostra; T Gasser; N W Wood; A Dürr
Journal:  J Med Genet       Date:  2004-12       Impact factor: 6.318

3.  Robustness and power of the maximum-likelihood-binomial and maximum-likelihood-score methods, in multipoint linkage analysis of affected-sibship data.

Authors:  L Abel; B Müller-Myhsok
Journal:  Am J Hum Genet       Date:  1998-08       Impact factor: 11.025

4.  Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III.

Authors:  D F Levinson; P Holmans; R E Straub; M J Owen; D B Wildenauer; P V Gejman; A E Pulver; C Laurent; K S Kendler; D Walsh; N Norton; N M Williams; S G Schwab; B Lerer; B J Mowry; A R Sanders; S E Antonarakis; J L Blouin; J F DeLeuze; J Mallet
Journal:  Am J Hum Genet       Date:  2000-08-02       Impact factor: 11.025

5.  New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study.

Authors:  F Cornélis; S Fauré; M Martinez; J F Prud'homme; P Fritz; C Dib; H Alves; P Barrera; N de Vries; A Balsa; D Pascual-Salcedo; K Maenaut; R Westhovens; P Migliorini; T H Tran; A Delaye; N Prince; C Lefevre; G Thomas; M Poirier; S Soubigou; O Alibert; S Lasbleiz; S Fouix; C Bouchier; F Lioté; M N Loste; V Lepage; D Charron; G Gyapay; A Lopes-Vaz; D Kuntz; T Bardin; J Weissenbach
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

6.  Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I early-onset proband: supportive evidence for linkage at 3p14.

Authors:  B Etain; F Mathieu; M Rietschel; W Maier; M Albus; P McKeon; S Roche; C Kealey; D Blackwood; W Muir; F Bellivier; C Henry; C Dina; S Gallina; H Gurling; A Malafosse; M Preisig; F Ferrero; S Cichon; J Schumacher; S Ohlraun; M Borrmann-Hassenbach; P Propping; R Abou Jamra; T G Schulze; A Marusic; Z M Dernovsek; B Giros; T Bourgeron; A Lemainque; D Bacq; C Betard; C Charon; M M Nöthen; M Lathrop; M Leboyer
Journal:  Mol Psychiatry       Date:  2006-03-14       Impact factor: 15.992

7.  The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes.

Authors:  S Ghosh; R M Watanabe; T T Valle; E R Hauser; V L Magnuson; C D Langefeld; D S Ally; K L Mohlke; K Silander; K Kohtamäki; P Chines; J Balow; G Birznieks; J Chang; W Eldridge; M R Erdos; Z E Karanjawala; J I Knapp; K Kudelko; C Martin; A Morales-Mena; A Musick; T Musick; C Pfahl; R Porter; J B Rayman
Journal:  Am J Hum Genet       Date:  2000-10-13       Impact factor: 11.043
  7 in total

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