| Literature DB >> 9433592 |
E W Pugh1, C E Jaquish, A J Sorant, J P Doetsch, J E Bailey-Wilson, A F Wilson.
Abstract
The statistical properties of sib-pair and variance-components linkage methods were compared using the nuclear family data from Problem 2. Overall, the power to detect linkage was not high for either method. The variance-components method had better power for detection of linkage, particularly when covariates were included in the model. Type I error rates were similar to nominal error rates for both methods.Mesh:
Substances:
Year: 1997 PMID: 9433592 DOI: 10.1002/(SICI)1098-2272(1997)14:6<867::AID-GEPI51>3.0.CO;2-K
Source DB: PubMed Journal: Genet Epidemiol ISSN: 0741-0395 Impact factor: 2.135