| Literature DB >> 9433129 |
M E Noble1, J A Endicott, N R Brown, L N Johnson.
Abstract
Regulation of both the cell cycle and gene transcription is essential for orderly progression of cell growth and division. Recent results on the structures of two cyclins, cyclin A and cyclin H, and two transcription factor mediator proteins, TFIIB and the A pocket region of the retinoblastoma tumour suppressor protein (Rb), show that they share domains with a strikingly similar alpha-helical topology, despite remote sequence identity.Entities:
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Year: 1997 PMID: 9433129 DOI: 10.1016/s0968-0004(97)01144-4
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807