| Literature DB >> 94325 |
H Suzuki, T Nishimura, N Tanaka.
Abstract
The mechanism of action of auromomycin was studied with intact cells of Bacillus subtilis. The antibiotic exhibited a preferential inhibition of DNA synthesis over RNA and protein syntheses. The strand scission of cellular DNA was induced by the drug, and DNA was degraded into acid-soluble fragments. The results suggested that DNA is the chemoreceptor of auromomycin.Entities:
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Year: 1979 PMID： 94325 DOI： 10.7164/antibiotics.32.706
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649