SETTING: Bouaké prison camp, Ivory Coast. OBJECTIVE: To determine the clinical, radiographic and therapeutic characteristics of smear-positive pulmonary tuberculosis in the prison camp of Bouaké. METHODS: The study included 108 cases of smear positive pulmonary tuberculosis who had never been treated previously. Triple chemotherapy of 6 months' duration was recommended for all of the patients. RESULTS: The incidence of smear positive tuberculosis in the prison population under study was very high (5.8%). In the majority of cases tuberculosis infection is associated with other conditions: here they were malnutrition (75%), anaemia (70%) and dermatoses (64%). Human immunodeficiency virus (HIV) infection was observed in 30% of the cases, and alcohol and tobacco dependence in 50%. Radiographic lesions were extensive in 70% of the cases. The 6-month treatment regimen is still effective: 80 of the 108 (74.1%) were cured, i.e. 97.6% of those who completed their treatment. The death rate, however, was alarming at 24% (one patient in four). The main reason for incarceration was theft (73%). CONCLUSION: Other epidemiological studies are needed urgently in order to pin-point those factors that favour the progression from tuberculous infection to disease in this very specific setting, and to improve socio-sanitary conditions for prison inmates.
SETTING: Bouaké prison camp, Ivory Coast. OBJECTIVE: To determine the clinical, radiographic and therapeutic characteristics of smear-positive pulmonary tuberculosis in the prison camp of Bouaké. METHODS: The study included 108 cases of smear positive pulmonary tuberculosis who had never been treated previously. Triple chemotherapy of 6 months' duration was recommended for all of the patients. RESULTS: The incidence of smear positive tuberculosis in the prison population under study was very high (5.8%). In the majority of cases tuberculosis infection is associated with other conditions: here they were malnutrition (75%), anaemia (70%) and dermatoses (64%). Human immunodeficiency virus (HIV) infection was observed in 30% of the cases, and alcohol and tobacco dependence in 50%. Radiographic lesions were extensive in 70% of the cases. The 6-month treatment regimen is still effective: 80 of the 108 (74.1%) were cured, i.e. 97.6% of those who completed their treatment. The death rate, however, was alarming at 24% (one patient in four). The main reason for incarceration was theft (73%). CONCLUSION: Other epidemiological studies are needed urgently in order to pin-point those factors that favour the progression from tuberculous infection to disease in this very specific setting, and to improve socio-sanitary conditions for prison inmates.
Authors: Amadeu A Vieira; Sandra A Ribeiro; Ana M de Siqueira; Vera M N Galesi; Laedi A R dos Santos; Jonathan E Golub Journal: Rev Bras Epidemiol Date: 2010-12
Authors: Y Merid; Y Woldeamanuel; M Abebe; D G Datiko; T Hailu; G Habtamu; G Assefa; R R Kempker; H M Blumberg; A Aseffa Journal: Int J Tuberc Lung Dis Date: 2018-05-01 Impact factor: 2.373
Authors: Iacopo Baussano; Brian G Williams; Paul Nunn; Marta Beggiato; Ugo Fedeli; Fabio Scano Journal: PLoS Med Date: 2010-12-21 Impact factor: 11.069
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Authors: Katie R Maggard; Sisa Hatwiinda; Jennifer B Harris; Winifreda Phiri; Annika Krüüner; Kaunda Kaunda; Stephanie M Topp; Nathan Kapata; Helen Ayles; Chisela Chileshe; German Henostroza; Stewart E Reid Journal: Bull World Health Organ Date: 2015-02-01 Impact factor: 9.408