Literature DB >> 943118

Effect of lithium and other alkali metals on brain chemistry and behavior. I. Glutamic acid and GABA in brain regions.

Z Gottesfeld.   

Abstract

Glutamic acid and GABA concentrations were measured in brain areas of rats injected with the chloride salts of Li+, Na+, K", Rb+ or Cs+ for 5 days. Regional changes in brain glutamic acid and GABA were found in animals after lithium, rubidium or cesium, but not potassium, compared to sodium treatments. Increased glutamic acid and GABA levels, caused by lithium and rubidium, were found in brain structures (hypothalamus and amygdala) known to be involved in emotional behavior. Whether these changes are associated with the effective use of lithium and, perhaps, of rubidium in affective disorders remains obscure.

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Year:  1976        PMID： 943118     DOI： 10.1007/bf00421134

Source DB:  PubMed          Journal:  Psychopharmacologia


  23 in total

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Authors:  H BARUK; P FABIANI
Journal:  Ann Med Psychol (Paris)       Date:  1962-12       Impact factor: 0.380

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Journal:  Pharmacol Rev       Date:  1957-03       Impact factor: 25.468

3.  Effect of lithium and other alkali metals on brain chemistry and behavior. II. Intracranial self-stimulation behavior.

Authors:  A Edelson; Z Gottesfeld; D Samuel; A Yuwiler
Journal:  Psychopharmacologia       Date:  1976-02-02

4.  GABA transport by nerve ending fractions of cat brain.

Authors:  S R Snodgrass; E T Hedley-Whyte; A V Lorenzo
Journal:  J Neurochem       Date:  1973-03       Impact factor: 5.372

5.  [Hyperglycemic actions of potassium, rubidium and cesium ions compared to their hypertensive actions].

Authors:  R Hazard; J R Boissier; P Moillé; M Bréteau
Journal:  C R Seances Soc Biol Fil       Date:  1967

Review 6.  Glutamate and gamma-aminobutyric acid in brain.

Authors:  K Krnjević
Journal:  Nature       Date:  1970-10-10       Impact factor: 49.962

7.  Glutamate and GABA levels and glutamate decarboxylase activity in brain regions of rats after prolonged treatment with alkali cations.

Authors:  Z Gottesfeld; D Samuel; Y Icekson
Journal:  Experientia       Date:  1973-05-01

8.  Catecholamines and affective disorders revised: a critical assessment.

Authors:  B Shopsin; S Wilk; G Sathananthan; S Gershon; K Davis
Journal:  J Nerv Ment Dis       Date:  1974-05       Impact factor: 2.254

9.  The effects of acute and prolonged lithium treatment on the distribution of electrolytes, potassium and sodium.

Authors:  A K Ho; S Gershon; L Pinckney
Journal:  Arch Int Pharmacodyn Ther       Date:  1970-07

10.  Effect of ions on stimulus-induced release of amino acids from mammalian brain slices.

Authors:  R I Katz; T N Chase; I J Kopin
Journal:  J Neurochem       Date:  1969-06       Impact factor: 5.372
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  5 in total

Review 1.  Effects of cesium on cellular systems.

Authors:  A Ghosh; A Sharma; G Talukder
Journal:  Biol Trace Elem Res       Date:  1993-08       Impact factor: 3.738

2.  Lithium effects on rat brain glucose metabolism in long-term lithium-treated rats studied in vivo.

Authors:  P Plenge
Journal:  Psychopharmacology (Berl)       Date:  1978-07-19       Impact factor: 4.530

3.  Urinary dicarboxylic acids in patients receiving lithium or rubidium salts.

Authors:  S E Hill; F A Jenner; C R Lee; C Paschalis; R J Pollitt; G A Sampson
Journal:  Psychopharmacology (Berl)       Date:  1979-09       Impact factor: 4.530

4.  Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions.

Authors:  R S Jope; J M Miller; T N Ferraro; T A Hare
Journal:  Neurochem Res       Date:  1989-09       Impact factor: 3.996

5.  Lithium-induced changes in the brain levels of free amino acids in stress-exposed rats.

Authors:  L Eroğlu; P Binyildiz; S Atamer-Simşek
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530
  5 in total

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