UNLABELLED: We present radiation dose estimates for 111In-pentetreotide. METHODS: Kinetic data were gathered in 10 subjects at two different sites. A compartmental model was used to fit the data, including retention, in three major organs and excretion. RESULTS: The data were consistent for the subjects at both sites. The organ receiving the highest dose was the kidneys (0.52 mGy/MBq); the effective dose equivalent was 0.1 mSv/MBq, and the effective dose was 0.073 mSv/MBq. CONCLUSION: The results of this study provide the basis for evaluation of radiation safety of this drug.
UNLABELLED: We present radiation dose estimates for 111In-pentetreotide. METHODS: Kinetic data were gathered in 10 subjects at two different sites. A compartmental model was used to fit the data, including retention, in three major organs and excretion. RESULTS: The data were consistent for the subjects at both sites. The organ receiving the highest dose was the kidneys (0.52 mGy/MBq); the effective dose equivalent was 0.1 mSv/MBq, and the effective dose was 0.073 mSv/MBq. CONCLUSION: The results of this study provide the basis for evaluation of radiation safety of this drug.
Authors: David Taïeb; Henri J Timmers; Elif Hindié; Benjamin A Guillet; Hartmut P Neumann; Martin K Walz; Giuseppe Opocher; Wouter W de Herder; Carsten C Boedeker; Ronald R de Krijger; Arturo Chiti; Adil Al-Nahhas; Karel Pacak; Domenico Rubello Journal: Eur J Nucl Med Mol Imaging Date: 2012-08-28 Impact factor: 9.236
Authors: Uta Eberlein; Jörn Hendrik Bröer; Charlot Vandevoorde; Paula Santos; Manuel Bardiès; Klaus Bacher; Dietmar Nosske; Michael Lassmann Journal: Eur J Nucl Med Mol Imaging Date: 2011-08-30 Impact factor: 9.236
Authors: B Brans; L Bodei; F Giammarile; O Linden; M Luster; W J G Oyen; J Tennvall Journal: Eur J Nucl Med Mol Imaging Date: 2007-05 Impact factor: 9.236
Authors: Tiantian Li; Edwin C I Ao; Bieke Lambert; Boudewijn Brans; Stefaan Vandenberghe; Greta S P Mok Journal: Theranostics Date: 2017-10-13 Impact factor: 11.556