| Literature DB >> 9428353 |
T Escudero1, C Fuster, M D Coll, J Egozcue.
Abstract
A sequential fluorescence in situ hybridization (FISH) technique is described. This method allows the detection of up to eighteen chromosome pairs in consecutive hybridizations (8 steps) on the same metaphase using centromeric, whole chromosome painting, and single copy DNA probes with different fluorochromes. The technique may be used with diagnostic purposes in cases with poor cytogenetic material.Mesh:
Year: 1998 PMID: 9428353 DOI: 10.1016/s0165-4608(97)00029-0
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN: 0165-4608