Literature DB >> 9427959

Possible role of transforming growth factor-beta in relapsing-remitting multiple sclerosis.

P B Carrieri1, V Provitera, R Bruno, M Perrella, G Tartaglia, A Busto, O Perrella.   

Abstract

Cerebrospinal fluid (CSF) and serum levels of transforming growth factor (TGF)-beta and soluble intercellular adhesion molecule-1 (sICAM-1) were evaluated in ten patients with definite multiple sclerosis (MS) of the relapsing-remitting type. CSF TGF-beta levels of MS patients in remission were significantly (p < 0.01) higher than of MS patients in active phase, and there was a significant inverse correlation (p < 0.05) between TGF-beta and slCAM-1 levels in the CSF of patients in both remitting and relapsing type. This is consistent with a possible down-regulation of TGF-beta on ICAM-1 expression and suggests a possible synthesis in the central nervous system of TGF-beta.

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Year:  1997        PMID： 9427959     DOI： 10.1080/01616412.1997.11740866

Source DB:  PubMed          Journal:  Neurol Res        ISSN： 0161-6412            Impact factor:   2.448


  6 in total

Review 1.  The role of TGF-β superfamily signaling in neurological disorders.

Authors:  Risa Kashima; Akiko Hata
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2018-01-01       Impact factor: 3.848

2.  The rs3761548 FOXP3 variant is associated with multiple sclerosis and transforming growth factor β1 levels in female patients.

Authors:  Tamires Flauzino; Daniela Frizon Alfieri; Wildea Lice de Carvalho Jennings Pereira; Sayonara Rangel Oliveira; Ana Paula Kallaur; Marcell Alysson Batisti Lozovoy; Damacio Ramón Kaimen-Maciel; Karen Brajão de Oliveira; Andrea Name Colado Simão; Edna Maria Vissoci Reiche
Journal:  Inflamm Res       Date:  2019-08-14       Impact factor: 4.575

3.  The effects of transplanted mesenchymal stem cells treated with 17-b estradiol on experimental autoimmune encephalomyelitis.

Authors:  Rahim Heidari Barchi Nezhad; Fateme Asadi; Seyyed Meysam Abtahi Froushani; Gholamhossein Hassanshahi; Ayat Kaeidi; Soudeh Khanamani Falahati-Pour; Zahra Hashemi; Mohammad Reza Mirzaei
Journal:  Mol Biol Rep       Date:  2019-09-25       Impact factor: 2.316

4.  TGF-β in Mice Ameliorates Experimental Autoimmune Encephalomyelitis in Regulating NK Cell Activity.

Authors:  J Xu; Y Wang; H Jiang; M Sun; J Gao; A Xie
Journal:  Cell Transplant       Date:  2019-05-29       Impact factor: 4.064

Review 5.  Nanomodulation of Macrophages in Multiple Sclerosis.

Authors:  Frances K Nally; Chiara De Santi; Claire E McCoy
Journal:  Cells       Date:  2019-06-05       Impact factor: 6.600

6.  The neuroprotective functions of transforming growth factor beta proteins.

Authors:  Arpád Dobolyi; Csilla Vincze; Gabriella Pál; Gábor Lovas
Journal:  Int J Mol Sci       Date:  2012-07-03       Impact factor: 6.208
  6 in total

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