Literature DB >> 9427487

Improving results of esophageal stenting: a study on 160 consecutive unselected patients.

A Segalin1, L Bonavina, A Carazzone, C Ceriani, A Peracchia.   

Abstract

BACKGROUND AND STUDY AIMS: Esophageal stenting is a valuable treatment in the management of malignant dysphagia. Recently, self-expanding stents have proved effective in reducing morbidity and mortality. The aim of this study was to evaluate the early and late results of esophageal stenting in a series of 160 consecutive unselected patients with unresectable esophageal and cardial carcinoma treated between November 1992 and December 1996. PATIENTS AND METHODS: The procedure was successful in 159 patients (99.4%). A traditional tube was employed in 84 patients (52.5%). Metallic self-expanding stents have been available since June 1993 and were used in 75 selected patients (46.9%). The tumor was located in the cervical, upper, middle and lower thoracic esophagus, and at the gastric cardia in 16, 16, 56, 22 and 34 patients, respectively. In the remaining 15 patients an esophagovisceral anastomosis was involved. Preoperative chemo- and/or radiotherapy were performed in 82 patients (51.3%).
RESULTS: Overall hospital morbidity was 11.3% (18/159) and included four dislodgments, four incomplete expansions of a self-expanding stent, two perforations, two incomplete sealings of a malignant respiratory tract fistula, two hemorrhages, two persistent foreign body sensations, one arrhythmia and one aspiration pneumonia. Hospital mortality was 1.3% (2/159) and was recorded in patients who underwent traditional intubation. At discharge, dysphagia was improved at least 2 degrees in 152 patients (96.8%). The overall long-term morbidity was 23.5% (37/157). Mean survival after the procedure was 4.7 months.
CONCLUSIONS: Intubation is a safe palliative procedure which can be performed with low morbidity and mortality rates. Self-expanding metallic stents have enhanced the indications and the outcomes of the procedure, resulting in the treatment of strictures where the placement of a traditional tube is difficult or technically impossible.

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Year:  1997        PMID: 9427487     DOI: 10.1055/s-2007-1004293

Source DB:  PubMed          Journal:  Endoscopy        ISSN: 0013-726X            Impact factor:   10.093


  5 in total

1.  Guidelines for the management of oesophageal and gastric cancer.

Authors:  W H Allum; S M Griffin; A Watson; D Colin-Jones
Journal:  Gut       Date:  2002-06       Impact factor: 23.059

2.  Covered nitinol stents for the treatment of esophageal strictures and leaks.

Authors:  Davide Bona; Letizia Laface; Luigi Bonavina; Emmanuele Abate; Moshe Schaffer; Ippazio Ugenti; Stefano Siboni; Rosaria Carrinola
Journal:  World J Gastroenterol       Date:  2010-05-14       Impact factor: 5.742

3.  Stents for Esophageal Disease.

Authors:  Frank M. Moses; Roy K.H. Wong
Journal:  Curr Treat Options Gastroenterol       Date:  2002-02

4.  Self-expandable metallic stent placement for patients with inoperable esophageal carcinoma: investigation of the influence of prior radiotherapy and chemotherapy.

Authors:  Yuko Iraha; Sadayuki Murayama; Takafumi Toita; Takashi Utsunomiya; Osamu Nagata; Tamaki Akamine; Kazuhiko Ogawa; Genki Adachi; Noboru Tanigawa
Journal:  Radiat Med       Date:  2006-05

5.  Evidence-based choice of esophageal stent for the palliative management of malignant dysphagia.

Authors:  Danny Yakoub; Ramy Fahmy; Thanos Athanasiou; Afshin Alijani; Christopher Rao; Ara Darzi; George B Hanna
Journal:  World J Surg       Date:  2008-09       Impact factor: 3.352

  5 in total

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