Literature DB >> 9425736

Regulatory feedback pathways in the thymus.

R Mehr1, A S Perelson, M Fridkis-Hareli, A Globerson.   

Abstract

The idea that thymocytopoiesis may be subject to feedback regulation by mature lymphocytes is proposed on the basis of recent data from in vitro experimental models. Analysis of the data using mathematical models, presented here by Ramit Mehr and colleagues, suggests possible feedback control mechanisms in T-cell development.

Mesh:

Year:  1997        PMID: 9425736     DOI: 10.1016/s0167-5699(97)01150-x

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  4 in total

1.  Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation.

Authors:  Sol Efroni; David Harel; Irun R Cohen
Journal:  Genome Res       Date:  2003-11       Impact factor: 9.043

2.  Effects of intrabone marrow-bone marrow transplantation plus adult thymus transplantation on survival of mice bearing leukemia.

Authors:  Yuming Zhang; Naoki Hosaka; Yunze Cui; Ming Shi; Ming Li; Qing Li; Susumu Ikehara
Journal:  Stem Cells Dev       Date:  2011-10-19       Impact factor: 3.272

3.  The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: A modeling investigation.

Authors:  Tina M Mitre; Massimo Pietropaolo; Anmar Khadra
Journal:  Math Biosci       Date:  2016-10-17       Impact factor: 2.144

4.  Understanding natural killer cell regulation by mathematical approaches.

Authors:  Carsten Watzl; Michal Sternberg-Simon; Doris Urlaub; Ramit Mehr
Journal:  Front Immunol       Date:  2012-12-12       Impact factor: 7.561

  4 in total

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