Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Molecular cloning and physical mapping of the daptomycin gene cluster from Streptomyces roseosporus.

Literature DB >> 9422604

Molecular cloning and physical mapping of the daptomycin gene cluster from Streptomyces roseosporus.

M A Mchenney¹, T J Hosted, B S Dehoff, P R Rosteck, R H Baltz.

Abstract

The daptomycin biosynthetic gene cluster of Streptomyces roseosporus was analyzed by Tn5099 mutagenesis, molecular cloning, partial DNA sequencing, and insertional mutagenesis with cloned segments of DNA. The daptomycin biosynthetic gene cluster spans at least 50 kb and is located about 400 to 500 kb from one end of the approximately 7,100-kb linear chromosome. We identified two peptide synthetase coding regions interrupted by a 10- to 20-kb region that may encode other functions in lipopeptide biosynthesis.

Entities: Chemical Species

Mesh：

Substances：

Year: 1998 PMID： 9422604 PMCID： PMC106860

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

31 in total

1. Amino acid activation and polymerization at modular multienzymes in nonribosomal peptide biosynthesis.

Authors: T Stein; J Vater
Journal: Amino Acids Date: 1996-09 Impact factor: 3.520

2. The multiple carrier model of nonribosomal peptide biosynthesis at modular multienzymatic templates.

Authors: T Stein; J Vater; V Kruft; A Otto; B Wittmann-Liebold; P Franke; M Panico; R McDowell; H R Morris
Journal: J Biol Chem Date: 1996-06-28 Impact factor: 5.157

Review 3. Engineered biosynthesis of peptide antibiotics.

Authors: T Stachelhaus; A Schneider; M A Marahiel
Journal: Biochem Pharmacol Date: 1996-07-26 Impact factor: 5.858

4. Rational design of peptide antibiotics by targeted replacement of bacterial and fungal domains.

Authors: T Stachelhaus; A Schneider; M A Marahiel
Journal: Science Date: 1995-07-07 Impact factor: 47.728

5. Use of rpsL for dominance selection and gene replacement in Streptomyces roseosporus.

Authors: T J Hosted; R H Baltz
Journal: J Bacteriol Date: 1997-01 Impact factor: 3.490

6. Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: the synthesis and evaluation of daptomycin (LY146032).

Authors: M Debono; B J Abbott; R M Molloy; D S Fukuda; A H Hunt; V M Daupert; F T Counter; J L Ott; C B Carrell; L C Howard
Journal: J Antibiot (Tokyo) Date: 1988-08 Impact factor: 2.649

7. Gene transfer and transposition mutagenesis in Streptomyces roseosporus: mapping of insertions that influence daptomycin or pigment production.

Authors: M A McHenney; R H Baltz
Journal: Microbiology Date: 1996-09 Impact factor: 2.777

8. Deacylation of A21978C, an acidic lipopeptide antibiotic complex, by Actinoplanes utahensis.

Authors: L D Boeck; D S Fukuda; B J Abbott; M Debono
Journal: J Antibiot (Tokyo) Date: 1988-08 Impact factor: 2.649

9. The Streptomyces lividans 66 chromosome contains a 1 MB deletogenic region flanked by two amplifiable regions.

Authors: M Redenbach; F Flett; W Piendl; I Glocker; U Rauland; O Wafzig; R Kliem; P Leblond; J Cullum
Journal: Mol Gen Genet Date: 1993-11

10. Physical map of the Streptomyces lividans 66 genome and comparison with that of the related strain Streptomyces coelicolor A3(2).

Authors: P Leblond; M Redenbach; J Cullum
Journal: J Bacteriol Date: 1993-06 Impact factor: 3.490

15 in total

1. Genomewide insertional mutagenesis in Streptomyces coelicolor reveals additional genes involved in morphological differentiation.

Authors: A M Gehring; J R Nodwell; S M Beverley; R Losick
Journal: Proc Natl Acad Sci U S A Date: 2000-08-15 Impact factor: 11.205

Review 2. Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters.

Authors: Richard H Baltz
Journal: J Ind Microbiol Biotechnol Date: 2010-05-14 Impact factor: 3.346

Review 3. Taxonomy, Physiology, and Natural Products of Actinobacteria.

Authors: Essaid Ait Barka; Parul Vatsa; Lisa Sanchez; Nathalie Gaveau-Vaillant; Cedric Jacquard; Jan P Meier-Kolthoff; Hans-Peter Klenk; Christophe Clément; Yder Ouhdouch; Gilles P van Wezel
Journal: Microbiol Mol Biol Rev Date: 2015-11-25 Impact factor: 11.056

Review 4. Mechanism of Action and Resistance to Daptomycin in Staphylococcus aureus and Enterococci.

Authors: William R Miller; Arnold S Bayer; Cesar A Arias
Journal: Cold Spring Harb Perspect Med Date: 2016-11-01 Impact factor: 6.915

5. Synthetic biology, genome mining, and combinatorial biosynthesis of NRPS-derived antibiotics: a perspective.

Authors: Richard H Baltz
Journal: J Ind Microbiol Biotechnol Date: 2017-12-29 Impact factor: 3.346

Review 6. The calcium-dependent lipopeptide antibiotics: structure, mechanism, & medicinal chemistry.

Authors: Thomas M Wood; Nathaniel I Martin
Journal: Medchemcomm Date: 2019-03-21 Impact factor: 3.597

7. Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporus.

Authors: Richard H Baltz; Paul Brian; Vivian Miao; Stephen K Wrigley
Journal: J Ind Microbiol Biotechnol Date: 2005-09-28 Impact factor: 3.346

8. A genomic sample sequence of the entomopathogenic bacterium Photorhabdus luminescens W14: potential implications for virulence.

Authors: R H Ffrench-Constant; N Waterfield; V Burland; N T Perna; P J Daborn; D Bowen; F R Blattner
Journal: Appl Environ Microbiol Date: 2000-08 Impact factor: 4.792

9. Indole-3-acetic acid biosynthesis is deficient in Gluconacetobacter diazotrophicus strains with mutations in cytochrome c biogenesis genes.

Authors: Sunhee Lee; M Flores-Encarnación; M Contreras-Zentella; L Garcia-Flores; J E Escamilla; Christina Kennedy
Journal: J Bacteriol Date: 2004-08 Impact factor: 3.490

10. Cloning large natural product gene clusters from the environment: piecing environmental DNA gene clusters back together with TAR.

Authors: Jeffrey H Kim; Zhiyang Feng; John D Bauer; Dimitris Kallifidas; Paula Y Calle; Sean F Brady
Journal: Biopolymers Date: 2010-09 Impact factor: 2.505