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Literature DB >> 9422258

Hyperthermic treatment of malignant diseases: current status and a view toward the future.

M W Dewhirst¹, L Prosnitz, D Thrall, D Prescott, S Clegg, C Charles, J MacFall, G Rosner, T Samulski, E Gillette, S LaRue.

Abstract

New studies in hyperthermia at the basic science, engineering, and clinical level have stimulated renewed enthusiasm for re-investigating its potential as an anticancer therapy. This article reviews the salient features of these recent results and points out areas for additional investigation. Highlighting these new results is the publication of several positive phase III trials for thermoradiotherapy compared to radiotherapy alone. Important highlights are the encouraging results using magnetic resonance imaging for noninvasive thermometry. If this technology is successfully implemented with real time power control it will revolutionize the clinical application of hyperthermia.

Entities: Disease

Mesh：

Year: 1997 PMID： 9422258

Source DB: PubMed Journal: Semin Oncol ISSN： 0093-7754 Impact factor: 4.929

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Cited

15 in total

1. Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo.

Authors: Shama Moktan; Eddie Perkins; Felix Kratz; Drazen Raucher
Journal: Mol Cancer Ther Date: 2012-04-24 Impact factor: 6.261

Review 2. Cell penetrating elastin-like polypeptides for therapeutic peptide delivery.

Authors: Gene L Bidwell; Drazen Raucher
Journal: Adv Drug Deliv Rev Date: 2010-05-15 Impact factor: 15.470

3. The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy.

Authors: Andrew R Burke; Ravi N Singh; David L Carroll; James C S Wood; Ralph B D'Agostino; Pulickel M Ajayan; Frank M Torti; Suzy V Torti
Journal: Biomaterials Date: 2012-01-14 Impact factor: 12.479

Review 4. Mild temperature hyperthermia and radiation therapy: role of tumour vascular thermotolerance and relevant physiological factors.

Authors: Robert J Griffin; Ruud P M Dings; Azemat Jamshidi-Parsian; Chang W Song
Journal: Int J Hyperthermia Date: 2010 Impact factor: 3.914

Hyperthermic treatment of malignant diseases: current status and a view toward the future.

1. Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo.

Review 2. Cell penetrating elastin-like polypeptides for therapeutic peptide delivery.

3. The resistance of breast cancer stem cells to conventional hyperthermia and their sensitivity to nanoparticle-mediated photothermal therapy.

Review 4. Mild temperature hyperthermia and radiation therapy: role of tumour vascular thermotolerance and relevant physiological factors.

Review 5. Drug delivery to solid tumors by elastin-like polypeptides.

Review 6. Present and future technology for simultaneous superficial thermoradiotherapy of breast cancer.

7. Short-duration-focused ultrasound stimulation of Hsp70 expression in vivo.

8. Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides.

9. Feasibility of A-mode ultrasound attenuation as a monitoring method of local hyperthermia treatment.

Review 10. Carbon nanotubes in hyperthermia therapy.