Literature DB >> 9421197

A novel 15-hydroxyeicosatrienoic acid-substituted diacylglycerol (15-HETrE-DAG) selectively inhibits epidermal protein kinase C-beta.

Y Cho1, V A Ziboh.   

Abstract

Diacylglycerol containing 15-hydroxyeicosatrienoic acid (15-HETrE-DAG) was biosynthesized and examined for modulation of epidermal protein kinase C (PKC) activity. 15-HETrE-DAG competitively inhibited diolein-activated total PKC activity in a dose-dependent manner and further, selectively inhibited epidermal PKC-beta activity.

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Year:  1997        PMID： 9421197     DOI： 10.1016/s0005-2760(97)00144-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  3 in total

1.  Epidermal anti-Inflammatory properties of 5,11,14 20:3: effects on mouse ear edema, PGE2 levels in cultured keratinocytes, and PPAR activation.

Authors:  Alvin Berger; Irina Monnard; Markus Baur; Corinne Charbonnet; Irina Safonova; André Jomard
Journal:  Lipids Health Dis       Date:  2002-12-06       Impact factor: 3.876

Review 2.  Mammalian Epidermis: A Compendium of Lipid Functionality.

Authors:  Matteo Vietri Rudan; Fiona M Watt
Journal:  Front Physiol       Date:  2022-01-12       Impact factor: 4.566

Review 3.  Multiple roles of dihomo-γ-linolenic acid against proliferation diseases.

Authors:  Xiaoping Wang; Huanping Lin; Yan Gu
Journal:  Lipids Health Dis       Date:  2012-02-14       Impact factor: 3.876
  3 in total

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