Comparison of tomographic and planar radionuclide ventriculography in the assessment of regional left ventricular function in patients with left ventricular aneurysm before and after surgery.

METHODS AND
RESULTS: To compare tomographic and planar radionuclide ventriculography (RNVG) in assessing regional left ventricular (LV) function and predicting improvement in LV ejection fraction (LVEF) after operation in patients with LV aneurysm, 18 patients with aneurysm underwent both tomography and planar RNVG 1 month before and 3 weeks to 6 months after aneurysmectomy and coronary artery bypass grafting. All patients also underwent preoperative contrast angiography at catheterization. The percent shortening of the apical, anterior, lateral, inferior, and basal segments was calculated from tomographic long-axis and short-axis slices and corresponding planar images (anterior and 30- and 70-degree left anterior oblique views). No significant differences in anterior, apical, and lateral percent shortening were apparent before aneurysmectomy between tomographic and planar studies. However, preoperative basal percent shortening was 47% +/- 13% from tomographic and 28% +/- 14% from planar images (p < 0.001). Preoperative tomography generally agreed better with contrast angiographic results than did planar imaging. After aneurysmectomy, basal function improved to 57% +/- 12% (p < 0.01) by tomography. For all patients, LVEF increased from 29% +/- 8% before to 38% +/- 9% (p < 0.01) after aneurysmectomy. However, the greatest improvement (31% +/- 11% to 41% +/- 9%; p < 0.01) was in the 15 patients with greater than 30% basal shortening by tomography before aneurysmectomy; in contrast, no change of LVEF occurred in the three patients with lesser preoperative basal percent shortening. Moreover, greater than 30% basal percent shortening by tomography before aneurysmectomy identified the group most likely to have an increase in LVEF of 5% or more from before to after aneurysmectomy. Prediction of postoperative results was not possible from preoperative planar data. Thus in patients with LV aneurysm, tomographic RNVG appears to provide information that is different and more accurately predictive of results after aneurysmectomy than that available from planar imaging.