| Literature DB >> 9420623 |
A J de Beaufort1, J A Langermans, A M Matze-van der Lans, P S Hiemstra, J M Vossen, R van Furth.
Abstract
The binding and opsonic properties of C-reactive protein (CRP) for various species of bacteria were investigated. CRP bound more avidly to killed than to live Streptococcus pneumoniae, the binding varying among various serotypes; CRP hardly bound to a number of other bacterial species studied. CRP enhanced complement-dependent phagocytosis of live S. pneumoniae by granulocytes but did not enhance the phagocytosis of live Staphylococcus aureus or group B streptococci. We suppose that CRP may serve as an opsonin for killed bacteria and bacterial debris but is probably not an important opsonin for live bacteria other than S. pneumoniae.Entities:
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Year: 1997 PMID： 9420623 DOI： 10.1046/j.1365-3083.1997.d01-171.x
Source DB: PubMed Journal: Scand J Immunol ISSN： 0300-9475 Impact factor: 3.487