Literature DB >> 9420240

The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses.

J M Bergelson1, A Krithivas, L Celi, G Droguett, M S Horwitz, T Wickham, R L Crowell, R W Finberg.   

Abstract

Complementary DNA clones encoding the murine homolog (mCAR) of the human coxsackievirus and adenovirus receptor (CAR) were isolated. Nonpermissive CHO cells transfected with mCAR cDNA became susceptible to infection by coxsackieviruses B3 and B4 and showed increased susceptibility to adenovirus-mediated gene transfer. These results indicate that the same receptor is responsible for virus interactions with both murine and human cells. Analysis of receptor expression in human and murine tissues should be useful in defining factors governing virus tropism in vivo.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9420240      PMCID： PMC109389     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  30 in total

Review 1.  CELLULAR SUSCEPTIBILITY TO ENTEROVIRUSES.

Authors:  C M KUNIN
Journal:  Bacteriol Rev       Date:  1964-12

2.  Virus-tissue union and the pathogenesis of enterovirus infections.

Authors:  C M KUNIN
Journal:  J Immunol       Date:  1962-05       Impact factor: 5.422

3.  Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types.

Authors:  T J Wickham; P W Roelvink; D E Brough; I Kovesdi
Journal:  Nat Biotechnol       Date:  1996-11       Impact factor: 54.908

4.  Comparative analysis of adenovirus fiber-cell interaction: adenovirus type 2 (Ad2) and Ad9 utilize the same cellular fiber receptor but use different binding strategies for attachment.

Authors:  P W Roelvink; I Kovesdi; T J Wickham
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

5.  A model system for in vivo gene transfer into the central nervous system using an adenoviral vector.

Authors:  B L Davidson; E D Allen; K F Kozarsky; J M Wilson; B J Roessler
Journal:  Nat Genet       Date:  1993-03       Impact factor: 38.330

6.  Direct interactions of coxsackievirus B3 with immune cells in the splenic compartment of mice susceptible or resistant to myocarditis.

Authors:  D R Anderson; J E Wilson; C M Carthy; D Yang; R Kandolf; B M McManus
Journal:  J Virol       Date:  1996-07       Impact factor: 5.103

7.  Virus-receptor interaction in an adenovirus system.

Authors:  L Philipson; K Lonberg-Holm; U Pettersson
Journal:  J Virol       Date:  1968-10       Impact factor: 5.103

8.  Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes.

Authors:  M A Morsy; E L Alford; A Bett; F L Graham; C T Caskey
Journal:  J Clin Invest       Date:  1993-09       Impact factor: 14.808

9.  Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo.

Authors:  Y Manome; P Y Wen; Y Dong; T Tanaka; B S Mitchell; D W Kufe; H A Fine
Journal:  Nat Med       Date:  1996-05       Impact factor: 53.440

10.  Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.

Authors:  Y Yang; F A Nunes; K Berencsi; E Gönczöl; J F Engelhardt; J M Wilson
Journal:  Nat Genet       Date:  1994-07       Impact factor: 38.330
View more
  91 in total

1.  rab5 GTPase regulates adenovirus endocytosis.

Authors:  T Rauma; J Tuukkanen; J M Bergelson; G Denning; T Hautala
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

2.  CAR-dependent and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts.

Authors:  C Hidaka; E Milano; P L Leopold; J M Bergelson; N R Hackett; R W Finberg; T J Wickham; I Kovesdi; P Roelvink; R G Crystal
Journal:  J Clin Invest       Date:  1999-02       Impact factor: 14.808

3.  Dependence of adenovirus infectivity on length of the fiber shaft domain.

Authors:  D M Shayakhmetov; A Lieber
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

4.  Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions.

Authors:  D A Einfeld; R Schroeder; P W Roelvink; A Lizonova; C R King; I Kovesdi; T J Wickham
Journal:  J Virol       Date:  2001-12       Impact factor: 5.103

5.  The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction.

Authors:  C J Cohen; J T Shieh; R J Pickles; T Okegawa; J T Hsieh; J M Bergelson
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-04       Impact factor: 11.205

6.  Adenovirus serotype 30 fiber does not mediate transduction via the coxsackie-adenovirus receptor.

Authors:  Lane K Law; Beverly L Davidson
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

7.  Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell types.

Authors:  Clare E Thomas; Penny Edwards; Thomas J Wickham; Maria G Castro; Pedro R Lowenstein
Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

Review 8.  Gene delivery into primary T cells: overview and characterization of a transgenic model for efficient adenoviral transduction.

Authors:  Vincent Hurez; Robin D Hautton; James Oliver; R James Matthews; Casey K Weaver
Journal:  Immunol Res       Date:  2002       Impact factor: 2.829

9.  A zebrafish coxsackievirus and adenovirus receptor homologue interacts with coxsackie B virus and adenovirus.

Authors:  JenniElizabeth Petrella; Christopher J Cohen; Jedidiah Gaetz; Jeffrey M Bergelson
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

10.  Usage of integrin and heparan sulfate as receptors for mouse adenovirus type 1.

Authors:  Sharmila Raman; Tien-Huei Hsu; Shanna L Ashley; Katherine R Spindler
Journal:  J Virol       Date:  2009-01-28       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.