Literature DB >> 9420053

Cloning and nucleotide sequence analysis of a gene encoding an OXA-derived beta-lactamase in Acinetobacter baumannii.

J Vila1, M Navia, J Ruiz, C Casals.   

Abstract

A clinical strain of Acinetobacter baumannii (strain Ab41) that was resistant to all beta-lactam antibiotics tested except ceftazidime, ceftriaxone, ceftizoxime, and imipenem produced three beta-lactamases: a presumptive chromosomal cephalosporinase, a TEM-1-like beta-lactamase (pI 5.4), and a novel OXA-derived beta-lactamase named OXA-21 (pI 7.0). The gene encoding OXA-21 was located in an integron. The nucleotide sequence showed three mutations compared with the sequence of OXA-3, with two being silent; the nonsilent mutation generated a substitution of Ile-217 to Met.

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Year:  1997        PMID： 9420053      PMCID： PMC164203     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

1.  Antimicrobial drug susceptibility of clinical isolates of Acinetobacter species (A. baumannii, A. haemolyticus, genospecies 3, and genospecies 6).

Authors:  W H Traub; M Spohr
Journal:  Antimicrob Agents Chemother       Date:  1989-09       Impact factor: 5.191

2.  Outer membrane permeability of Acinetobacter calcoaceticus and its implication in antibiotic resistance.

Authors:  K Sato; T Nakae
Journal:  J Antimicrob Chemother       Date:  1991-07       Impact factor: 5.790

3.  Immunological comparison between OXA-2 beta-lactamase and those mediated by other R plasmids.

Authors:  S Holland; J W Dale
Journal:  Antimicrob Agents Chemother       Date:  1985-06       Impact factor: 5.191

Review 4.  Epidemiology of nosocomial infections due to Acinetobacter calcoaceticus.

Authors:  E Bergogne-Bérézin; M L Joly-Guillou; J F Vieu
Journal:  J Hosp Infect       Date:  1987-09       Impact factor: 3.926

5.  Antimicrobial susceptibility of clinical isolates of Acinetobacter baumannii.

Authors:  Z Y Shi; P Y Liu; Y Lau; Y Lin; B S Hu
Journal:  Diagn Microbiol Infect Dis       Date:  1996-02       Impact factor: 2.803

6.  The use of analytical isoelectric focusing for detection and identification of beta-lactamases.

Authors:  A Mathew; A M Harris; M J Marshall; G W Ross
Journal:  J Gen Microbiol       Date:  1975-05

7.  Antimicrobial susceptibility of Acinetobacter species.

Authors:  H Seifert; R Baginski; A Schulze; G Pulverer
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

8.  In vitro antimicrobial production of beta-lactamases, aminoglycoside-modifying enzymes, and chloramphenicol acetyltransferase by and susceptibility of clinical isolates of Acinetobacter baumannii.

Authors:  J Vila; A Marcos; F Marco; S Abdalla; Y Vergara; R Reig; R Gomez-Lus; T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1993-01       Impact factor: 5.191

Review 9.  Nosocomial acinetobacter meningitis secondary to invasive procedures: report of 25 cases and review.

Authors:  Y Siegman-Igra; S Bar-Yosef; A Gorea; J Avram
Journal:  Clin Infect Dis       Date:  1993-11       Impact factor: 9.079

10.  Laboratory investigation of hospital outbreak caused by two different multiresistant Acinetobacter calcoaceticus subsp. anitratus strains.

Authors:  J Vila; M Almela; M T Jimenez de Anta
Journal:  J Clin Microbiol       Date:  1989-05       Impact factor: 5.948
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  20 in total

Review 1.  Extended-spectrum beta-lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat.

Authors:  P A Bradford
Journal:  Clin Microbiol Rev       Date:  2001-10       Impact factor: 26.132

2.  Cloning, nucleotide sequencing, and analysis of the gene encoding an AmpC beta-lactamase in Acinetobacter baumannii.

Authors:  G Bou; J Martínez-Beltrán
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

3.  Class 1 Integrons in Salmonella Strains causing traveler's diarrhea.

Authors:  Roberto Cabrera; Francesc Marco; Jordi Vila; Joaquím Ruiz; Joaquím Gascón
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

4.  Comparative analysis of antimicrobial resistance in enterotoxigenic Escherichia coli isolates from two paediatric cohort studies in Lima, Peru.

Authors:  Anicia M Medina; Fulton P Rivera; Maria J Pons; Maribel Riveros; Cláudia Gomes; María Bernal; Rina Meza; Ryan C Maves; Luis Huicho; Elsa Chea-Woo; Claudio F Lanata; Ana I Gil; Theresa J Ochoa; Joaquim Ruiz
Journal:  Trans R Soc Trop Med Hyg       Date:  2015-08       Impact factor: 2.184

5.  Virulence factors and mechanisms of antimicrobial resistance in Shigella strains from periurban areas of Lima (Peru).

Authors:  Angela Lluque; Susan Mosquito; Cláudia Gomes; Maribel Riveros; David Durand; Drake H Tilley; María Bernal; Ana Prada; Theresa J Ochoa; Joaquim Ruiz
Journal:  Int J Med Microbiol       Date:  2015-05-04       Impact factor: 3.473

6.  Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian hospitals reveals a limited diversity of gene cassette arrays.

Authors:  Francesca Gombac; Maria Letizia Riccio; Gian Maria Rossolini; Cristina Lagatolla; Enrico Tonin; Carlo Monti-Bragadin; Annamaria Lavenia; Lucilla Dolzani
Journal:  Antimicrob Agents Chemother       Date:  2002-11       Impact factor: 5.191

7.  Novel class A beta-lactamase Sed-1 from Citrobacter sedlakii: genetic diversity of beta-lactamases within the Citrobacter genus.

Authors:  S Petrella; D Clermont; I Casin; V Jarlier; W Sougakoff
Journal:  Antimicrob Agents Chemother       Date:  2001-08       Impact factor: 5.191

8.  OXA-24, a novel class D beta-lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain.

Authors:  G Bou; A Oliver; J Martínez-Beltrán
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

9.  Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii.

Authors:  X Corbella; A Montero; M Pujol; M A Domínguez; J Ayats; M J Argerich; F Garrigosa; J Ariza; F Gudiol
Journal:  J Clin Microbiol       Date:  2000-11       Impact factor: 5.948

10.  Nosocomial transmission of CTX-M-2 beta-lactamase-producing Acinetobacter baumannii in a neurosurgery ward.

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Journal:  J Clin Microbiol       Date:  2004-09       Impact factor: 5.948
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