Literature DB >> 9418087

Comparison of cost effectiveness of directly observed treatment (DOT) and conventionally delivered treatment for tuberculosis: experience from rural South Africa.

K Floyd1, D Wilkinson, C Gilks.   

Abstract

OBJECTIVE: To conduct an economic evaluation of directly observed treatment (DOT) and conventionally delivered treatment for the management of new cases of tuberculosis in adults.
DESIGN: Community based directly observed treatment, which has been implemented in the Hlabisa district of South Africa since 1991, was compared with a conventional approach to tuberculosis treatment widely used in Africa. Each was assessed in terms of cost, cost effectiveness, and feasibility of implementation within existing resource constraints.
SETTING: Hlabisa Health District, South Africa.
SUBJECTS: Adult patients with new cases of tuberculosis on smear testing; the number of cases increased from 20 per month to over 100 from 1991 to 1996. MAIN OUTCOME MEASURES: Cost of case management in 1996, cost effectiveness in terms of the cost per case cured, and bed requirements in comparison with bed availability for the 1990, 1993, and 1996 caseload. Costs are expressed in US dollars at values for 1996.
RESULTS: Directly observed treatment was 2.8 times cheaper overall than conventional treatment ($740.90 compared with $2047.70) to deliver. Directly observed treatment worked out 2.4-4.2 times more cost effective, costing $890.50 per patient cured compared with either $2095.60 (best case) or $3700.40 (worst case) for conventional treatment. The 1996 caseload of tuberculosis required 47 beds to be dedicated to tuberculosis to implement directly observed treatment, whereas conventionally delivered treatment would have required 160 beds; the current number of beds for tuberculosis treatment in Hlabisa is fixed at 56.
CONCLUSIONS: Because of the reduced stay in hospital, directly observed treatment is cheaper, more cost effective, and more feasible than conventional treatment in managing tuberculosis in Hlabisa, given the existing hospital bed capacity and the escalating caseload due to the HIV/AIDS epidemic. Such results may hold elsewhere, and wherever conventional tuberculosis management is practised a switch to directly observed treatment will increase hospital capacity to cope with a growing caseload.

Entities:  

Keywords:  Africa; Africa South Of The Sahara; Cost Effectiveness; Demographic Factors; Developing Countries; Diseases; English Speaking Africa; Evaluation; Evaluation Indexes; Infections; Population; Population Characteristics; Quantitative Evaluation; Research Report; Rural Population; South Africa; Southern Africa; Treatment--cost; Tuberculosis

Mesh:

Year:  1997        PMID: 9418087      PMCID: PMC2127898          DOI: 10.1136/bmj.315.7120.1407

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  24 in total

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Authors:  L P Ormerod
Journal:  Thorax       Date:  1999-08       Impact factor: 9.139

2.  The long-term health and economic benefits of DOTS implementation in Ecuador.

Authors:  Olivia Oxlade; Judyth Vaca; Elizabeth Romero; Kevin Schwartzman; Brian Graham; Lucero Hernandez; Terry Tannenbaum; Dick Menzies
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3.  Community based programmes can help to manage tuberculosis more effectively.

Authors:  R de Soldenhoff
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Review 4.  Pharmacokinetic factors in the modern drug treatment of tuberculosis.

Authors:  J G Douglas; M J McLeod
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5.  Can Malawi's poor afford free tuberculosis services? Patient and household costs associated with a tuberculosis diagnosis in Lilongwe.

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6.  Occurrence of female genital tuberculosis among infertile women: a study from a tertiary maternal health care research centre in South India.

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7.  Tuberculosis-related deaths within a well-functioning DOTS control program.

Authors:  Maria De Lourdes García-García; Alfredo Ponce-De-León; Maria Cecilia García-Sancho; Leticia Ferreyra-Reyes; Manuel Palacios-Martínez; Javier Fuentes; Midori Kato-Maeda; Miriam Bobadilla; Peter Small; José Sifuentes-Osornio
Journal:  Emerg Infect Dis       Date:  2002-11       Impact factor: 6.883

8.  Measuring Catastrophic Costs Due to Tuberculosis in Myanmar.

Authors:  Si Thu Aung; Aung Thu; Htin Lin Aung; Min Thu
Journal:  Trop Med Infect Dis       Date:  2021-07-14

9.  The indirect cost due to pulmonary Tuberculosis in patients receiving treatment in Bauchi State-Nigeria.

Authors:  Nisser Ali Umar; Richard Fordham; Ibrahim Abubakar; Max Bachmann
Journal:  Cost Eff Resour Alloc       Date:  2012-05-11

Review 10.  Tuberculosis and poverty: the contribution of patient costs in sub-Saharan Africa--a systematic review.

Authors:  Devra M Barter; Stephen O Agboola; Megan B Murray; Till Bärnighausen
Journal:  BMC Public Health       Date:  2012-11-14       Impact factor: 3.295

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