OBJECTIVE: To evaluate the value of a systematic approach to the diagnosis of pediatric interstitial lung disease (ILD). METHODS: In this descriptive, observational, prospective study, we evaluated 51 children presenting with ILD of unknown etiology during a 3-year period. Specific clinical information regarding history, physical examination, diagnostic evaluation, and final diagnosis was recorded on each patient. RESULTS: A specific diagnosis was established by history and physical examination alone in 1 patient, noninvasive tests alone in 8 others, and invasive tests, including lung biopsy, in another 26. Of the remaining patients, 8 had a suggestive diagnosis, and 8 had no specific diagnosis. CONCLUSIONS: A systematic approach to the diagnosis of pediatric ILD is useful, and not all patients need lung biopsy for diagnosis.
OBJECTIVE: To evaluate the value of a systematic approach to the diagnosis of pediatric interstitial lung disease (ILD). METHODS: In this descriptive, observational, prospective study, we evaluated 51 children presenting with ILD of unknown etiology during a 3-year period. Specific clinical information regarding history, physical examination, diagnostic evaluation, and final diagnosis was recorded on each patient. RESULTS: A specific diagnosis was established by history and physical examination alone in 1 patient, noninvasive tests alone in 8 others, and invasive tests, including lung biopsy, in another 26. Of the remaining patients, 8 had a suggestive diagnosis, and 8 had no specific diagnosis. CONCLUSIONS: A systematic approach to the diagnosis of pediatric ILD is useful, and not all patients need lung biopsy for diagnosis.
Authors: Jennifer J Soares; Gail H Deutsch; Paul E Moore; Mohammad F Fazili; Eric D Austin; Rebekah F Brown; Andrew G Sokolow; Melissa A Hilmes; Lisa R Young Journal: Pediatrics Date: 2013-09-30 Impact factor: 7.124
Authors: Leland L Fan; Megan K Dishop; Csaba Galambos; Frederic B Askin; Frances V White; Claire Langston; Deborah R Liptzin; Miranda E Kroehl; Gail H Deutsch; Lisa R Young; Geoffrey Kurland; James Hagood; Sharon Dell; Bruce C Trapnell; Robin R Deterding Journal: Ann Am Thorac Soc Date: 2015-10
Authors: Geoffrey Kurland; Robin R Deterding; James S Hagood; Lisa R Young; Alan S Brody; Robert G Castile; Sharon Dell; Leland L Fan; Aaron Hamvas; Bettina C Hilman; Claire Langston; Lawrence M Nogee; Gregory J Redding Journal: Am J Respir Crit Care Med Date: 2013-08-01 Impact factor: 21.405
Authors: Gail H Deutsch; Lisa R Young; Robin R Deterding; Leland L Fan; Sharon D Dell; Judy A Bean; Alan S Brody; Lawrence M Nogee; Bruce C Trapnell; Claire Langston; Eric A Albright; Frederic B Askin; Peter Baker; Pauline M Chou; Carlyne M Cool; Susan C Coventry; Ernest Cutz; Mary M Davis; Megan K Dishop; Csaba Galambos; Kathleen Patterson; William D Travis; Susan E Wert; Frances V White Journal: Am J Respir Crit Care Med Date: 2007-09-20 Impact factor: 21.405
Authors: S Balasubramanian; Lalitha Janakiraman; R Ganesh; M Deenadayalan; Radhika K Naidu Journal: Indian J Pediatr Date: 2007-07 Impact factor: 1.967