Literature DB >> 9415870

The role of innovation in drug development.

J Drews1, S Ryser.   

Abstract

Mesh:

Year:  1997        PMID: 9415870     DOI: 10.1038/nbt1297-1318

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN: 1087-0156            Impact factor:   54.908


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  21 in total

1.  Waiting for the working draft from the human genome project. A huge achievement, but not of immediate medical use.

Authors:  L R Cardon; H Watkins
Journal:  BMJ       Date:  2000-05-06

2.  Topological side-chain classification of beta-turns: ideal motifs for peptidomimetic development.

Authors:  Tran Trung Tran; Jim McKie; Wim D F Meutermans; Gregory T Bourne; Peter R Andrews; Mark L Smythe
Journal:  J Comput Aided Mol Des       Date:  2005-11-23       Impact factor: 3.686

3.  Meta-basic estimates the size of druggable human genome.

Authors:  Dariusz Plewczynski; Leszek Rychlewski
Journal:  J Mol Model       Date:  2008-07-29       Impact factor: 1.810

4.  The inadequacy of the reductionist approach in discovering new therapeutic agents against complex diseases.

Authors:  Manuel X Duval
Journal:  Exp Biol Med (Maywood)       Date:  2018-08-08

Review 5.  Conducting clinical research in community mental health settings: Opportunities and challenges.

Authors:  Oleg V Tcheremissine; Whitney E Rossman; Manuel A Castro; Dineen R Gardner
Journal:  World J Psychiatry       Date:  2014-09-22

Review 6.  The discovery of first-in-class drugs: origins and evolution.

Authors:  Jörg Eder; Richard Sedrani; Christian Wiesmann
Journal:  Nat Rev Drug Discov       Date:  2014-07-18       Impact factor: 84.694

Review 7.  Dynamic conformational flexibility and molecular interactions of intrinsically disordered proteins.

Authors:  Anil Bhattarai; Isaac Arnold Emerson
Journal:  J Biosci       Date:  2020       Impact factor: 1.826

Review 8.  Computational systems chemical biology.

Authors:  Tudor I Oprea; Elebeoba E May; Andrei Leitão; Alexander Tropsha
Journal:  Methods Mol Biol       Date:  2011

9.  Investigation of copper-cysteamine nanoparticles as a new photosensitizer for anti-hepatocellular carcinoma.

Authors:  Xuejing Huang; Fengjie Wan; Lun Ma; Jonathan B Phan; Rebecca Xueyi Lim; Cuiping Li; Jiagui Chen; Jinghuan Deng; Yasi Li; Wei Chen; Min He
Journal:  Cancer Biol Ther       Date:  2019-02-06       Impact factor: 4.742

Review 10.  Removing obstacles in neuroscience drug discovery: the future path for animal models.

Authors:  Athina Markou; Christian Chiamulera; Mark A Geyer; Mark Tricklebank; Thomas Steckler
Journal:  Neuropsychopharmacology       Date:  2008-10-01       Impact factor: 7.853

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