Literature DB >> 9415119

Relationship between susceptibility to protein oxidation, aging, and maximum life span potential of different species.

S Agarwal1, R S Sohal.   

Abstract

The main objective of this study was to determine whether antioxidative potential of the tissues plays a role in the aging process. Antioxidative potential was ascertained as the susceptibility of tissues to undergo protein oxidation, manifested as protein carbonyls, in response to acute oxidative stress, induced by exposure to x-rays. Brain homogenates from 22-month-old rats were more susceptible to oxidative stress than those from three-month-old rats. Brain was more susceptible to oxidative damage than the heart. A comparison of the susceptibility of brain and heart homogenates in five different species (mouse, rat, rabbit, pig, and pigeon) indicated that maximum life span potential of the species was inversely related to their susceptibility to acute oxidative stress.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 9415119     DOI： 10.1016/0531-5565(95)02039-x

Source DB:  PubMed          Journal:  Exp Gerontol        ISSN： 0531-5565            Impact factor:   4.032


  16 in total

Review 1.  Oxidative stress, caloric restriction, and aging.

Authors:  R S Sohal; R Weindruch
Journal:  Science       Date:  1996-07-05       Impact factor: 47.728

Review 2.  Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging.

Authors:  R Weindruch; R S Sohal
Journal:  N Engl J Med       Date:  1997-10-02       Impact factor: 91.245

Review 3.  Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent.

Authors:  Karl A Rodriguez; Ewa Wywial; Viviana I Perez; Adriant J Lambert; Yael H Edrey; Kaitlyn N Lewis; Kelly Grimes; Merry L Lindsey; Martin D Brand; Rochelle Buffenstein
Journal:  Curr Pharm Des       Date:  2011       Impact factor: 3.116

4.  Nuclear-mitochondrial epistasis and drosophila aging: introgression of Drosophila simulans mtDNA modifies longevity in D. melanogaster nuclear backgrounds.

Authors:  David M Rand; Adam Fry; Lea Sheldahl
Journal:  Genetics       Date:  2005-10-11       Impact factor: 4.562

5.  Spatial memory is enhanced in long-living Ames dwarf mice and maintained following kainic acid induced neurodegeneration.

Authors:  Sunita Sharma; James Haselton; Sharlene Rakoczy; Stephanie Branshaw; Holly M Brown-Borg
Journal:  Mech Ageing Dev       Date:  2010-06-16       Impact factor: 5.432

Review 6.  The redox stress hypothesis of aging.

Authors:  Rajindar S Sohal; William C Orr
Journal:  Free Radic Biol Med       Date:  2011-10-24       Impact factor: 7.376

7.  Accumulation of mtDNA variations in human single CD34+ cells from maternally related individuals: effects of aging and family genetic background.

Authors:  Yong-Gang Yao; Sachiko Kajigaya; Xingmin Feng; Leigh Samsel; J Philip McCoy; Giuseppe Torelli; Neal S Young
Journal:  Stem Cell Res       Date:  2013-01-29       Impact factor: 2.020

Review 8.  Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.

Authors:  D Allan Butterfield; Fabio Di Domenico; Aaron M Swomley; Elizabeth Head; Marzia Perluigi
Journal:  Biochem J       Date:  2014-10-15       Impact factor: 3.857

Review 9.  Caloric restriction and the aging process: a critique.

Authors:  Rajindar S Sohal; Michael J Forster
Journal:  Free Radic Biol Med       Date:  2014-06-02       Impact factor: 7.376

10.  The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis.

Authors:  Adam B Salmon; Shanique Leonard; Venkata Masamsetti; Anson Pierce; Andrej J Podlutsky; Natalia Podlutskaya; Arlan Richardson; Steven N Austad; Asish R Chaudhuri
Journal:  FASEB J       Date:  2009-02-24       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.