Literature DB >> 9413701

Vitamin supplementation therapy in the elderly.

J E Thurman1, A D Mooradian.   

Abstract

Vitamin supplementation in large dosages is increasingly common in the older population. Often, such supplementation is used in an attempt to improve an individual's health status. There have been claims that the effects of vitamins halt the normal aging process or prevent and cure disease. However, several recent studies have failed to demonstrate the efficacy of vitamin supplementation in preventing several types of cancer. In moderate dosages, supplementation with vitamin E (tocopherols) shows promise as a lipid antioxidant, and may reduce the risk of coronary heart disease. However, before vitamin E becomes an accepted medical therapy, further long term studies must be undertaken to examine the safety and efficacy of such therapy. An adequate intake of vitamins should be ensured by adherence to a well balanced diet. However, the elderly are prone to circumstances that may prevent them from eating a balanced diet. In addition, there are several age-related medical conditions that may predispose individuals to dietary and vitamin deficiencies. To prevent vitamin deficiency diseases and their associated morbidity, modest vitamin supplementation may be necessary. However, supplementation should be reserved for individuals with documented deficiency or who are at risk of developing such deficiencies, especially those who are homebound or institutionalised. Vitamins taken in large dosages should be considered as drugs. These medicines, which are obtainable over-the-counter, should be carefully regulated to prevent toxicity.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9413701     DOI: 10.2165/00002512-199711060-00003

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  148 in total

Review 1.  Newly identified actions of the vitamin D endocrine system.

Authors:  M R Walters
Journal:  Endocr Rev       Date:  1992-11       Impact factor: 19.871

2.  Destruction of vitamin B12 by ascorbic acid.

Authors:  V Herbert; E Jacob
Journal:  JAMA       Date:  1974-10-14       Impact factor: 56.272

3.  Ascorbic acid causes spuriously low blood glucose measurements.

Authors:  J G Strijdom; B J Marais; J H Koeslag
Journal:  S Afr Med J       Date:  1993-01

4.  Low serum folic acid levels in a nursing home population: a clinical experience.

Authors:  P J Drinka; E H Langer; S K Voeks; J S Goodwin
Journal:  J Am Coll Nutr       Date:  1993-04       Impact factor: 3.169

5.  Thiamine, thiamine phosphates, and their metabolizing enzymes in human brain.

Authors:  L Bettendorff; F Mastrogiacomo; S J Kish; T Grisar
Journal:  J Neurochem       Date:  1996-01       Impact factor: 5.372

6.  Vitamin E consumption and the risk of coronary disease in women.

Authors:  M J Stampfer; C H Hennekens; J E Manson; G A Colditz; B Rosner; W C Willett
Journal:  N Engl J Med       Date:  1993-05-20       Impact factor: 91.245

Review 7.  More folic acid for everyone, now.

Authors:  G P Oakley; M J Adams; C M Dickinson
Journal:  J Nutr       Date:  1996-03       Impact factor: 4.798

8.  Effect of vitamin E and beta carotene on the incidence of angina pectoris. A randomized, double-blind, controlled trial.

Authors:  J M Rapola; J Virtamo; J K Haukka; O P Heinonen; D Albanes; P R Taylor; J K Huttunen
Journal:  JAMA       Date:  1996-03-06       Impact factor: 56.272

9.  Biochemical factors in the lens opacities. Case-control study. The Lens Opacities Case-Control Study Group.

Authors:  M C Leske; S Y Wu; L Hyman; R Sperduto; B Underwood; L T Chylack; R C Milton; S Srivastava; N Ansari
Journal:  Arch Ophthalmol       Date:  1995-09

10.  Descriptive epidemiology of colorectal cancer.

Authors:  P Boyle; D G Zaridze; M Smans
Journal:  Int J Cancer       Date:  1985-07-15       Impact factor: 7.396

View more
  6 in total

1.  Vitamin or supplement use among adults, behavioral risk factor surveillance system, 13 states, 2001.

Authors:  Lina S Balluz; Catherine A Okoro; Barbara A Bowman; Mary K Serdula; Ali H Mokdad
Journal:  Public Health Rep       Date:  2005 Mar-Apr       Impact factor: 2.792

Review 2.  Chronic actinic dermatitis in the elderly: recognition and treatment.

Authors:  Robert S Dawe
Journal:  Drugs Aging       Date:  2005       Impact factor: 3.923

Review 3.  Antioxidant vitamins and their influence in diabetes mellitus.

Authors:  Bibi Hasanain; Arshag D Mooradian
Journal:  Curr Diab Rep       Date:  2002-10       Impact factor: 4.810

Review 4.  Evidence-Based Management of Diabetes in Older Adults.

Authors:  Arshag D Mooradian
Journal:  Drugs Aging       Date:  2018-12       Impact factor: 3.923

Review 5.  Vitamin C and Immune Function.

Authors:  Anitra C Carr; Silvia Maggini
Journal:  Nutrients       Date:  2017-11-03       Impact factor: 5.717

Review 6.  Zinc, Vitamin D and Vitamin C: Perspectives for COVID-19 With a Focus on Physical Tissue Barrier Integrity.

Authors:  José João Name; Ana Carolina Remondi Souza; Andrea Rodrigues Vasconcelos; Pietra Sacramento Prado; Carolina Parga Martins Pereira
Journal:  Front Nutr       Date:  2020-12-07
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.