Transmission, species specificity, and pathogenicity of Aujeszky's disease virus.

Aujeszky's disease virus (ADV), also known as pseudorabies virus (PrV), is an alphaherpesvirus that causes fatal infections in a wide range of animal species. The virus shares a variety of biological properties with human pathogenic herpesviruses like herpes simplex virus or varicella-zoster virus. Although only limited data are available, it seems unlikely that PrV causes disease in immunocompetent humans, but may pose a risk for immunocompromised patients.