| Literature DB >> 9413042 |
T Murata1, S Nakamura, H Kato, Y Yatabe, T Shiraishi, M Kuroda, R Yatani, T Suchi.
Abstract
A case of Hodgkin's disease (HD), lymphocyte depression (LD) type in an immunosuppressive patient is described. The patient was a 48-year-old male and his parents were born in the Kyushu area, which is an endemic area for adult T cell lymphoma/leukemia (ATL). He was seropositive for ATL virus (ATLV, also referred to as HTLV-I) and showed a marked immunosuppressive condition. He developed LD-HD and Pneumocystis carinii pneumonia, and died due to respiratory failure. The immunohistochemical and in situ hybridization analyses revealed that the Reed-Sternberg-like cells in the lymph node biopsy sample were positive for Ber-H2 (CD30), Leu-M1 (CD15), L-26 (CD20), Bcl-2, p53 and EBER, the viral genome of Epstein-Barr virus (EBV).Entities:
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Year: 1997 PMID： 9413042 DOI： 10.1111/j.1440-1827.1997.tb04461.x
Source DB: PubMed Journal: Pathol Int ISSN： 1320-5463 Impact factor: 2.534