| Literature DB >> 941180 |
A M Hossain, D N Kirk, G Mitra.
Abstract
The first convenient chemical synthesis of 7alpha-hydroxyandrost-4-ene-3,17-dione is reported. Androsta-4,6-diene3, 17-dione was converted into its 6alpha, 7alpha-epoxy-derivative; reduction of the epoxide with aluminum amalgam gave 7alpha-hydroxyandrost-4-ene-3,17-dione. This reducing agent is more efficient than chromous acetate for the purpose.Entities:
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Year: 1976 PMID： 941180 DOI： 10.1016/s0039-128x(76)90096-9
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668