Literature DB >> 9408668

The effect of botulinum toxin on hand function after incomplete spinal cord injury at the level of C5/6: a case report.

D Richardson1, S Edwards, G L Sheean, R J Greenwood, A J Thompson.   

Abstract

OBJECTIVE: To investigate the benefits of the focal use of botulinum toxin in spasticity in the forearm seen after incomplete spinal cord injury.
DESIGN: A single case study with standardized assessment before and at three-week intervals after injection. INTERVENTION: EMG-guided selective injection of botulinum toxin. SUBJECT: A 23-year-old man, 18 months post injury. MEASURES: Rivermead Motor Assessment; grip strength; Jebsen hand tests; visual analogue scale; Ashworth spasticity scale.
RESULTS: Weakness was seen as expected with some functional losses, but the patient made gains in the areas of concern: shaking hands, typing, using the hand to drink. These gains were sustained at 12 weeks.
CONCLUSION: Selective use of botulinum toxin to weaken muscles can lead to functional benefit.

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Year:  1997        PMID: 9408668     DOI: 10.1177/026921559701100404

Source DB:  PubMed          Journal:  Clin Rehabil        ISSN: 0269-2155            Impact factor:   3.477


  4 in total

1.  Treatment of spasticity in spinal cord injury with botulinum toxin.

Authors:  Ramiro Palazón-García; Mónica Alcobendas-Maestro; Ana Esclarin-de Ruz; Ana María Benavente-Valdepeñas
Journal:  J Spinal Cord Med       Date:  2018-06-05       Impact factor: 1.985

Review 2.  Botulinum Toxin and Neuronal Regeneration after Traumatic Injury of Central and Peripheral Nervous System.

Authors:  Siro Luvisetto
Journal:  Toxins (Basel)       Date:  2020-07-02       Impact factor: 4.546

Review 3.  Botulinum Toxin: From Poison to Possible Treatment for Spasticity in Spinal Cord Injury.

Authors:  Ramiro Palazón-García; Ana María Benavente-Valdepeñas
Journal:  Int J Mol Sci       Date:  2021-05-05       Impact factor: 5.923

4.  Upper limb international spasticity study: rationale and protocol for a large, international, multicentre prospective cohort study investigating management and goal attainment following treatment with botulinum toxin A in real-life clinical practice.

Authors:  Lynne Turner-Stokes; Klemens Fheodoroff; Jorge Jacinto; Pascal Maisonobe; Benjamin Zakine
Journal:  BMJ Open       Date:  2013-03-18       Impact factor: 2.692

  4 in total

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