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Literature DB >> 9407560

Identification of Protoceratium reticulatum as the biogenetic origin of yessotoxin.

Abstract

Yessotoxin (YTX), a disulfated polyether toxin, was isolated from cultured cells of the marine dinoflagellate Protoceratium reticulatum and unambiguously identified by high-performance liquid chromatography, 1H NMR, and MS data. The result is the first to confirm toxigenicity of this species and demonstrate it as one of the biogenetic origins of YTX found in shellfish.

Entities: Chemical Species

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Year: 1997 PMID： 9407560 DOI： 10.1002/nt.7

Source DB: PubMed Journal: Nat Toxins ISSN： 1056-9014

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Cited

21 in total

1. Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and β-amyloid pathology.

Authors: Eva Alonso; Carmen Vale; Mercedes R Vieytes; Luis M Botana
Journal: ACS Chem Neurosci Date: 2013-04-08 Impact factor: 4.418

2. Effect of yessotoxin on cytosolic calcium levels in human hepatocellular carcinoma cells in vitro.

Authors: Min Pang; Pei Qu; Chun-Lei Gao; Xuexi Tang; Zong-Ling Wang
Journal: Biomed Rep Date: 2013-11-19

3. Use of biosensors as alternatives to current regulatory methods for marine biotoxins.

Authors: Natalia Vilariño; Eva S Fonfría; M Carmen Louzao; Luis M Botana
Journal: Sensors (Basel) Date: 2009-11-24 Impact factor: 3.576

Review 4. Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species.

Authors: Rossella Pistocchi; Franca Guerrini; Laura Pezzolesi; Manuela Riccardi; Silvana Vanucci; Patrizia Ciminiello; Carmela Dell'Aversano; Martino Forino; Ernesto Fattorusso; Luciana Tartaglione; Anna Milandri; Marinella Pompei; Monica Cangini; Silvia Pigozzi; Elena Riccardi
Journal: Mar Drugs Date: 2012-01-17 Impact factor: 6.085

Identification of Protoceratium reticulatum as the biogenetic origin of yessotoxin.

1. Translocation of PKC by yessotoxin in an in vitro model of Alzheimer's disease with improvement of tau and β-amyloid pathology.

2. Effect of yessotoxin on cytosolic calcium levels in human hepatocellular carcinoma cells in vitro.

3. Use of biosensors as alternatives to current regulatory methods for marine biotoxins.

Review 4. Toxin levels and profiles in microalgae from the north-Western Adriatic Sea--15 years of studies on cultured species.

5. Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins.

6. Different toxic effects of YTX in tumor K-562 and lymphoblastoid cell lines.

7. Occurrence of lipophilic marine toxins in shellfish from Galicia (NW of Spain) and synergies among them.

8. Selective disruption of the E-cadherin-catenin system by an algal toxin.

9. Report on the first detection of pectenotoxin-2, spirolide-a and their derivatives in French shellfish.

Review 10. Yessotoxins, a group of marine polyether toxins: an overview.