Literature DB >> 9406008

Influence of sex and chronic haemodialysis treatment on total, free and acyl carnitine concentrations in human serum.

A S Alhomida1, S H Sobki, M H al-Sulaiman, A A al-Khader.   

Abstract

The influence of sex and haemodialysis treatment on serum total, free and acyl carnitine concentrations in healthy controls and chronic renal failure patients has been investigated. Patients on regular haemodialysis treatment generally displayed significantly decreased serum carnitine levels. The mean predialysis serum carnitine levels were not significantly different from the mean healthy control values. However, after dialysis a significant decrease in serum carnitine levels was observed compared to the predialysis and healthy control values. Moreover, serum ratio of acylated to free carnitine was significantly higher after haemodialysis as compared to both healthy controls and predialysis patients. Sex-related changes in serum total, free and acyl carnitine levels and ratios of acylated to free carnitine have been observed in healthy controls and patients on chronic haemodialysis treatment.

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Year:  1997        PMID： 9406008     DOI： 10.1007/bf02551117

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN： 0301-1623            Impact factor:   2.370


  14 in total

Review 1.  Carnitine.

Authors:  L L Bieber
Journal:  Annu Rev Biochem       Date:  1988       Impact factor: 23.643

2.  Primary carnitine deficiency due to a failure of carnitine transport in kidney, muscle, and fibroblasts.

Authors:  W R Treem; C A Stanley; D N Finegold; D E Hale; P M Coates
Journal:  N Engl J Med       Date:  1988-11-17       Impact factor: 91.245

Review 3.  Carnitine metabolism in chronic renal failure.

Authors:  G Guarnieri; G Toigo; L Crapesi; R Situlin; M A Del Bianco; M Corsi; P LoGreco; G Paviotti; G Mioni; L Campanacci
Journal:  Kidney Int Suppl       Date:  1987-10       Impact factor: 10.545

4.  A comparison of plasma and muscle carnitine levels in patients on peritoneal or hemodialysis for chronic renal failure.

Authors:  A V Moorthy; M Rosenblum; R Rajaram; A L Shug
Journal:  Am J Nephrol       Date:  1983 Jul-Aug       Impact factor: 3.754

5.  Plasma and muscle carnitine levels in haemodialysis patients with morphological-ultrastructural examination of muscle samples.

Authors:  V Savica; G Bellinghieri; C Di Stefano; E Corvaja; F Consolo; M Corsi; F Maccari; L G Spagnoli; S Villaschi; G Palmieri
Journal:  Nephron       Date:  1983       Impact factor: 2.847

6.  Carnitine deficiency induced during hemodialysis and hyperlipidemia: effect of replacement therapy.

Authors:  M Bertoli; P A Battistella; L Vergani; A Naso; M L Gasparotto; G F Romagnoli; C Angelini
Journal:  Am J Clin Nutr       Date:  1981-08       Impact factor: 7.045

7.  Quantitative assessment of carnitine loss during hemodialysis and hemofiltration.

Authors:  M Leschke; K W Rumpf; T Eisenhauer; C Fuchs; K Becker; U Köthe; F Scheler
Journal:  Kidney Int Suppl       Date:  1983-12       Impact factor: 10.545

8.  Carnitine deficiency induced during intermittent haemodialysis for renal failure.

Authors:  T Bohmer; H Bergrem; K Eiklid
Journal:  Lancet       Date:  1978-01-21       Impact factor: 79.321

9.  Carnitine metabolism in patients with chronic renal failure: effect of L-carnitine supplementation.

Authors:  C Wanner; S Förstner-Wanner; C Rössle; P Fürst; P Schollmeyer; W H Hörl
Journal:  Kidney Int Suppl       Date:  1987-10       Impact factor: 10.545

10.  Hepatic synthesis of carnitine from protein-bound trimethyl-lysine. Lysosomal digestion of methyl-lysine-labelled asialo-fetuin.

Authors:  J LaBadie; W A Dunn; N N Aronson
Journal:  Biochem J       Date:  1976-10-15       Impact factor: 3.857
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