PURPOSE: To determine the role of indocyanine green angiography (ICGA) in the prediction of the development of choroidal neovascularization (CNV). METHODS: We reviewed the ICG angiograms of 124 patients with newly diagnosed unilateral occult CNV secondary to age-related macular degeneration (AMD) in whom the fellow eye had only drusen by biomicroscopy and fluorescein angiography. Follow-up data of at least 12 months were obtained in all eyes. RESULTS: 113 fellow eyes had a normal ICG study, while 11 fellow eyes revealed plaque-like late hyperfluorescence. During an average follow-up time of 18.2 months exudative AMD developed in 7 of 11 eyes with late hyperfluorescence on ICGA and in 6 of 113 with a normal ICGA study. CONCLUSION: ICGA may help to predict which fellow eyes are at higher risk of developing future exudative changes.
PURPOSE: To determine the role of indocyanine green angiography (ICGA) in the prediction of the development of choroidal neovascularization (CNV). METHODS: We reviewed the ICG angiograms of 124 patients with newly diagnosed unilateral occult CNV secondary to age-related macular degeneration (AMD) in whom the fellow eye had only drusen by biomicroscopy and fluorescein angiography. Follow-up data of at least 12 months were obtained in all eyes. RESULTS: 113 fellow eyes had a normal ICG study, while 11 fellow eyes revealed plaque-like late hyperfluorescence. During an average follow-up time of 18.2 months exudative AMD developed in 7 of 11 eyes with late hyperfluorescence on ICGA and in 6 of 113 with a normal ICGA study. CONCLUSION: ICGA may help to predict which fellow eyes are at higher risk of developing future exudative changes.
Authors: Jin Yang; Qinqin Zhang; Elie H Motulsky; Marie Thulliez; Yingying Shi; Cancan Lyu; Luis de Sisternes; Mary K Durbin; William Feuer; Ruikang K Wang; Giovanni Gregori; Philip J Rosenfeld Journal: Am J Ophthalmol Date: 2019-06-21 Impact factor: 5.258
Authors: Burhan Hameed; David M Smith; Jon J Verrechio; J David Schmidt; Leesa E Gillooley; Mary Carmen Valenzano; Simon A Lewis; James M Mullin Journal: Dig Dis Sci Date: 2004-09 Impact factor: 3.199
Authors: Mengxi Shen; Qinqin Zhang; Jin Yang; Hao Zhou; Zhongdi Chu; Xiao Zhou; William Feuer; Xiaoshuang Jiang; Yingying Shi; Luis de Sisternes; Mary K Durbin; Ruikang K Wang; Giovanni Gregori; Philip J Rosenfeld Journal: Invest Ophthalmol Vis Sci Date: 2021-05-03 Impact factor: 4.799